SCHEMBL21670541

SCHEMBL21670541

COc1ccc(-c2cc(-c3ccc(Nc4ccccc4)cc3)cc(-c3ccc(OC)cc3OC)n2)c(OC)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.52
KMT2A Q03164 5/20 0.52
NPC1 O15118 4/20 0.52
RAB9A P51151 4/20 0.52
MAPT P10636 3/20 0.52
SMN1; SMN2 Q16637 3/20 0.52
NFKB1 P19838 2/20 0.52
NFKB2 Q00653 2/20 0.52
RELA Q04206 2/20 0.52
ATM Q13315 1/20 0.52
KDM4E B2RXH2 2/20 0.49
CSNK2A1 P68400 1/20 0.49
POLB P06746 1/20 0.49
ALDH1A1 P00352 2/20 0.47
TP53 P04637 2/20 0.47
HTT P42858 1/20 0.47
HSD17B10 Q99714 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
ACP1 P24666 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30525969 1.00 MEN1 (0.52) MEN1KMT2ANPC1RAB9AMAPT
Diphenylamine SCHEMBL8196609 0.96 KMT2A (0.56) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL30525956 0.90 KMT2A (0.44) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL21670526 0.90 KMT2A (0.44) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL21670529 0.87 CYP1A2 (0.49) ALDH1A1HSD17B10CYP1A2CYP3A4CYP2D6
SCHEMBL21670550 0.86 FGFR2 (0.45) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL29048655 0.86 FGFR2 (0.50) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL30525978 0.86 FGFR2 (0.45) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL21670539 0.85 ADORA2A (0.45) MEN1KMT2AMAPTKDM4EALDH1A1
SCHEMBL30525993 0.85 ADORA2A (0.45) MEN1KMT2AMAPTKDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3608386-B1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN PILOT INK CO LTD (JP) 2025-02-19 EP disclosed
US-11060018-B2 Reversibly thermochromic composition and reversibly thermochromic microcapsule pigment encapsulating the same THE PILOT INK CO., LTD. (JP) 2021-07-13 US disclosed
US-20200048542-A1 REVERSIBLY THERMOCHROMIC COMPOSITION AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT ENCAPSULATING THE SAME THE PILOT INK CO., LTD. (JP) 2020-02-13 US disclosed
EP-3608386-A1 REVERSIBLY THERMOCHROMIC COMPOSITION, AND REVERSIBLY THERMOCHROMIC MICROCAPSULE PIGMENT HAVING SAME ENCLOSED THEREIN The Pilot Ink Co., Ltd (JP) 2020-02-12 EP disclosed