Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | ELANE | P08246 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | BCL2 | P10415 | 3/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | MAOA | P21397 | 3/20 | 0.36 |
| ▸ | RECQL | P46063 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | APEX1 | P27695 | 2/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12402088 | 0.81 | ADORA2A (0.47) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL1038701 | 0.81 | ALDH1A1 (0.66) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8593971 | 0.76 | MAPT (0.55) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL11141653 | 0.70 | MAPT (0.49) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL496910 | 0.70 | ELANE (0.60) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL22827087 | 0.68 | MAPT (0.86) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL10663800 | 0.68 | MAPT (0.68) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9296477 | 0.68 | ADORA2A (0.48) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL9297115 | 0.68 | ADORA2A (0.55) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL8583274 | 0.68 | MAPT (0.71) | MAPTALDH1A1MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8277695-B2 | Reversibly thermochromic compositions | BASF SE (DE) | 2012-10-02 | — | — | US | disclosed |
| EP-2032657-B1 | REVERSIBLY THERMOCHROMIC COMPOSITIONS | BASF SE (DE) | 2011-08-10 | — | — | EP | disclosed |
| US-20110180767-A1 | Reversibly thermochromic compositions | CIBA CORPORATION | 2011-07-28 | — | — | US | disclosed |
| EP-2032657-A2 | REVERSIBLY THERMOCHROMIC COMPOSITIONS | Ciba Holding Inc. (CH) | 2009-03-11 | — | — | EP | disclosed |
| WO-2007147847-A2 | REVERSIBLY THERMOCHROMIC COMPOSITIONS | CIBA HOLDING INC. (CH) | 2007-12-27 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110180767-A1 | Reversibly thermochromic compositions | C1R, C3AR1, C9 | MAPT 55/4885ALDH1A1 2451/4885MEN1 1208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.