SCHEMBL21671255

SCHEMBL21671255

CCC(C)(C)c1ccc(C(C)(CC)N=C=S)cc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.40
RAB9A P51151 3/20 0.40
MAPT P10636 1/20 0.40
LMNA P02545 1/20 0.34
MAPK1 P28482 1/20 0.34
CASP3 P42574 1/20 0.34
ATM Q13315 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
SENP8 Q96LD8 1/20 0.34
SENP7 Q9BQF6 1/20 0.34
SENP6 Q9GZR1 1/20 0.34
CNR2 P34972 2/20 0.33
SHBG P04278 1/20 0.33
HRH3 Q9Y5N1 10/20 0.33
MAOB P27338 8/20 0.33
ADORA3 P0DMS8 1/20 0.32
CHRM1 P11229 1/20 0.32
DRD3 P35462 1/20 0.32
KCNH2 Q12809 1/20 0.32
GABRA1 P14867 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21945875 0.87 TSHR (0.37) LMNASMN1; SMN2GABRA1GABRB2POLB
SCHEMBL21946062 0.87 NPC1 (0.41) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL23709134 0.81 NPC1 (0.40) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL21172815 0.80 TSHR (0.31) LMNA
SCHEMBL779443 0.74 NPC1 (0.58) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL8850555 0.72 GABRA1 (0.36) NPC1RAB9ALMNAMAPK1CASP3
SCHEMBL6675119 0.71 MIF (0.31) GABRA1GABRB2
SCHEMBL5552840 0.68 NPC1 (0.52) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL3625528 0.68 NPC1 (0.52) NPC1RAB9AMAPTLMNAMAPK1
SCHEMBL3292125 0.68 NPC1 (0.52) NPC1RAB9AMAPTLMNAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11201403-B2 Liquid crystal cell and scanning antenna SHARP KABUSHIKI KAISHA (JP) 2021-12-14 US disclosed
US-11005157-B2 Liquid crystal cell and scanning antenna SHARP KABUSHIKI KAISHA (JP) 2021-05-11 US disclosed
US-20200303817-A1 LIQUID CRYSTAL CELL AND SCANNING ANTENNA SHARP KABUSHIKI KAISHA (JP) 2020-09-24 US disclosed
US-20200044307-A1 LIQUID CRYSTAL CELL AND SCANNING ANTENNA SHARP KABUSHIKI KAISHA (JP) 2020-02-06 US disclosed