SCHEMBL21671473

SCHEMBL21671473

c1ccc2c(c1)c1ccccc1n2-c1ccc2c(c1)c1ccccc1n2-c1ccc(-n2c3ccccc3c3c(-n4c5ccccc5c5ccccc54)cccc32)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.48
L3MBTL1 Q9Y468 2/20 0.48
ATM Q13315 1/20 0.48
ALDH1A1 P00352 4/20 0.39
JAK2 O60674 1/20 0.33
JAK3 P52333 1/20 0.33
PTPN1 P18031 2/20 0.33
EDNRB P24530 1/20 0.33
EDNRA P25101 1/20 0.33
HDAC4 P56524 1/20 0.32
MEN1 O00255 3/20 0.32
KMT2A Q03164 3/20 0.32
HSD17B10 Q99714 3/20 0.32
MAPT P10636 2/20 0.32
HPGD P15428 2/20 0.32
HTT P42858 2/20 0.32
KDR P35968 1/20 0.31
MAPK1 P28482 1/20 0.31
HBB P68871 1/20 0.31
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26201464 0.97 L3MBTL1 (0.55) KDM4EL3MBTL1ATMALDH1A1JAK2
SCHEMBL25757284 0.97 L3MBTL1 (0.55) KDM4EL3MBTL1ATMALDH1A1JAK2
SCHEMBL15275570 0.97 L3MBTL1 (0.55) KDM4EL3MBTL1ATMALDH1A1JAK2
SCHEMBL15275589 0.97 L3MBTL1 (0.55) KDM4EL3MBTL1ATMALDH1A1JAK2
SCHEMBL19849236 0.97 L3MBTL1 (0.55) KDM4EL3MBTL1ATMALDH1A1JAK2
SCHEMBL25010822 0.97 L3MBTL1 (0.55) KDM4EL3MBTL1ATMALDH1A1JAK2
SCHEMBL15275572 0.97 L3MBTL1 (0.55) KDM4EL3MBTL1ATMALDH1A1JAK2
SCHEMBL19342619 0.95 L3MBTL1 (0.53) KDM4EL3MBTL1ATMALDH1A1JAK2
SCHEMBL15275586 0.95 KDM4E (0.47) KDM4EL3MBTL1ATMALDH1A1JAK2
SCHEMBL15275578 0.95 KDM4E (0.47) KDM4EL3MBTL1ATMALDH1A1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11374178-B2 Organic electroluminescent element NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2022-06-28 US disclosed
EP-3605634-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL Chemical & Material Co., Ltd. (JP) 2020-02-05 EP disclosed