SCHEMBL21671477

SCHEMBL21671477

c1ccc2c(c1)c1ccccc1n2-c1ccc(-n2c3ccccc3c3cccc(-n4c5ccccc5c5ccccc54)c32)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.57
L3MBTL1 Q9Y468 2/20 0.57
ATM Q13315 1/20 0.57
ALDH1A1 P00352 3/20 0.44
ALKBH5 Q6P6C2 1/20 0.39
FTO Q9C0B1 1/20 0.39
DUSP3 P51452 1/20 0.38
PTPN1 P18031 2/20 0.36
GPR3 P46089 1/20 0.35
HDAC4 P56524 1/20 0.35
CYP1A2 P05177 1/20 0.34
CYP2C19 P33261 1/20 0.34
POLB P06746 2/20 0.34
KMT2A Q03164 3/20 0.33
MAPK8 P45983 2/20 0.33
MEN1 O00255 2/20 0.33
MAPT P10636 2/20 0.33
HTT P42858 2/20 0.33
IL1R1 P14778 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22843267 0.98 KDM4E (0.54) KDM4EL3MBTL1ATMALDH1A1ALKBH5
SCHEMBL12447641 0.93 L3MBTL1 (0.48) KDM4EL3MBTL1ATMALDH1A1ALKBH5
SCHEMBL21671297 0.92 L3MBTL1 (0.63) KDM4EL3MBTL1ATMALDH1A1ALKBH5
SCHEMBL12447557 0.92 L3MBTL1 (0.63) KDM4EL3MBTL1ATMALDH1A1ALKBH5
SCHEMBL12447547 0.92 L3MBTL1 (0.63) KDM4EL3MBTL1ATMALDH1A1ALKBH5
SCHEMBL21671472 0.92 KDM4E (0.48) KDM4EL3MBTL1ATMALDH1A1ALKBH5
SCHEMBL12447560 0.91 KDM4E (0.50) KDM4EL3MBTL1ATMALDH1A1ALKBH5
SCHEMBL20232372 0.91 L3MBTL1 (0.61) KDM4EL3MBTL1ATMALDH1A1ALKBH5
SCHEMBL25396233 0.90 KDM4E (0.46) KDM4EL3MBTL1ATMALDH1A1ALKBH5
SCHEMBL21671374 0.89 KDM4E (0.53) KDM4EL3MBTL1ATMALDH1A1ALKBH5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11374178-B2 Organic electroluminescent element NIPPON STEEL CHEMICAL & MATERIAL CO., LTD. (JP) 2022-06-28 US disclosed
EP-3605634-A1 ORGANIC ELECTROLUMINESCENT ELEMENT NIPPON STEEL Chemical & Material Co., Ltd. (JP) 2020-02-05 EP disclosed