Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 16/20 | 0.54 |
| ▸ | MAP3K13 | O43283 | 1/20 | 0.48 |
| ▸ | DLK1 | P80370 | 1/20 | 0.48 |
| ▸ | ADK | P55263 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 2/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17076749 | 1.00 | MAP3K12 (0.54) | MAP3K12MAP3K13DLK1ADKMTOR | |
| SCHEMBL25147712 | 0.85 | MAP3K12 (0.50) | MAP3K12MAP3K13DLK1ADK | |
| SCHEMBL15743920 | 0.85 | MAP3K12 (0.50) | MAP3K12MAP3K13DLK1ADK | |
| SCHEMBL15743911 | 0.85 | MAP3K12 (0.50) | MAP3K12MAP3K13DLK1ADK | |
| SCHEMBL18307132 | 0.82 | MAP3K12 (0.48) | MAP3K12MAP3K13DLK1ADK | |
| SCHEMBL21588369 | 0.82 | ADK (0.49) | MAP3K12MAP3K13DLK1ADK | |
| SCHEMBL21588292 | 0.82 | ADK (0.49) | MAP3K12MAP3K13DLK1ADK | |
| SCHEMBL18307182 | 0.82 | MAP3K12 (0.48) | MAP3K12MAP3K13DLK1ADK | |
| SCHEMBL26794864 | 0.82 | MAP3K12 (0.48) | MAP3K12MAP3K13DLK1ADK | |
| SCHEMBL26794869 | 0.82 | MAP3K12 (0.48) | MAP3K12MAP3K13DLK1ADK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12528810-B2 | Small molecule inhibitors of DYRK/CLK and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2026-01-20 | — | — | US | disclosed |
| US-20250051325-A1 | SMALL MOLECULE INHIBITORS OF DYRK/CLK AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2025-02-13 | — | — | US | disclosed |
| US-12054483-B2 | Small molecule inhibitors of DYRK/CLK and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2024-08-06 | — | — | US | disclosed |
| US-20220041590-A1 | SMALL MOLECULE INHIBITORS OF DYRK/CLK AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2022-02-10 | — | — | US | disclosed |
| US-20200039989-A1 | SMALL MOLECULE INHIBITORS OF DYRK/CLK AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12528810-B2 | Small molecule inhibitors of DYRK/CLK and uses thereof | CLK3, CLK2, CLK1 | MAP3K12 128/4885MAP3K13 157/4885DLK1 484/4885 |
| US-20200039989-A1 | SMALL MOLECULE INHIBITORS OF DYRK/CLK AND USES THEREOF | CLK2, CLK1, CLK3 | MAP3K12 80/4885MAP3K13 147/4885DLK1 546/4885 |
| US-20220041590-A1 | SMALL MOLECULE INHIBITORS OF DYRK/CLK AND USES THEREOF | CLK2, CLK1, CLK3 | MAP3K12 80/4885MAP3K13 147/4885DLK1 546/4885 |
| US-12054483-B2 | Small molecule inhibitors of DYRK/CLK and uses thereof | CLK2, CLK1, CLK3 | MAP3K12 80/4885MAP3K13 147/4885DLK1 546/4885 |
| US-20250051325-A1 | SMALL MOLECULE INHIBITORS OF DYRK/CLK AND USES THEREOF | CLK2, CLK1, CLK3 | MAP3K12 80/4885MAP3K13 147/4885DLK1 546/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.