Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY2 | P41231 | 16/20 | 0.62 |
| ▸ | P2RY6 | Q15077 | 7/20 | 0.58 |
| ▸ | P2RY4 | P51582 | 7/20 | 0.58 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.55 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5068300 | 0.89 | P2RY2 (0.63) | P2RY2P2RY6P2RY4ENPP1P2RY14 | |
| SCHEMBL607048 | 0.88 | P2RY2 (0.62) | P2RY2P2RY6P2RY4ENPP1P2RY14 | |
| SCHEMBL8440687 | 0.88 | P2RY2 (0.62) | P2RY2P2RY6P2RY4ENPP1P2RY14 | |
| SCHEMBL18770063 | 0.88 | P2RY2 (0.62) | P2RY2P2RY6P2RY4ENPP1P2RY14 | |
| SCHEMBL30612530 | 0.88 | P2RY2 (0.62) | P2RY2P2RY6P2RY4ENPP1P2RY14 | |
| SCHEMBL622268 | 0.87 | P2RY2 (0.62) | P2RY2P2RY6P2RY4P2RY14 | |
| SCHEMBL622267 | 0.87 | P2RY2 (0.62) | P2RY2P2RY6P2RY4P2RY14 | |
| SCHEMBL8440925 | 0.86 | P2RY2 (0.60) | P2RY2P2RY6P2RY4P2RY14 | |
| SCHEMBL2800171 | 0.86 | P2RY2 (0.61) | P2RY2P2RY6P2RY4P2RY14 | |
| SCHEMBL8437839 | 0.85 | P2RY2 (0.61) | P2RY2P2RY6P2RY4P2RY14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7985541-B2 | Quantitative assay for detection of newly synthesized RNA in a cell-free system and identification of RNA synthesis inhibitors | ACHILLION PHARMACEUTICALS, INC. (US) | 2011-07-26 | — | — | US | disclosed |
| EP-1735470-B1 | QUANTITATIVE ASSAY FOR DETECTION OF NEWLY SYNTHESIZED RNA IN A CELL-FREE SYSTEM AND IDENTIFICATION OF RNA SYNTHESIS INHIBITORS | ACHILLION PHARMACEUTICALS INC (US) | 2010-04-21 | — | — | EP | disclosed |
| US-20070141558-A1 | Quantitative assay for detection of newly synthesized rna in a cell-free system and indentification of rna synthesis inhibitors | ACHILLION PHARMACEUTICALS, INC. | 2007-06-21 | — | — | US | disclosed |
| EP-1735470-A1 | QUANTITATIVE ASSAY FOR DETECTION OF NEWLY SYNTHESIZED RNA IN A CELL-FREE SYSTEM AND IDENTIFICATION OF RNA SYNTHESIS INHIBITORS | Achillion Pharmaceuticals, Inc. (US) | 2006-12-27 | — | — | EP | disclosed |
| WO-2005095655-A1 | QUANTITATIVE ASSAY FOR DETECTION OF NEWLY SYNTHESIZED RNA IN A CELL-FREE SYSTEM AND IDENTIFICATION OF RNA SYNTHESIS INHIBITORS | ACHILLION PHARMACEUTICALS, INC. (US) | 2005-10-13 | — | — | WO | disclosed |