SCHEMBL607048

SCHEMBL607048

O=c1ccn([C@@H]2O[C@H](C(F)OP(=O)(O)OP(=O)(O)OP(=O)(O)O)[C@@H](O)[C@H]2O)c(=O)[nH]1

nearest known ligand 0.62

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
P2RY2 P41231 15/20 0.62
P2RY6 Q15077 8/20 0.58
P2RY4 P51582 7/20 0.58
P2RY14 Q15391 2/20 0.53
ENPP1 P22413 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18770063 1.00 P2RY2 (0.62) P2RY2P2RY6P2RY4P2RY14ENPP1
SCHEMBL2800171 0.98 P2RY2 (0.61) P2RY2P2RY6P2RY4P2RY14
SCHEMBL2176028 0.90 P2RY2 (0.57) P2RY2P2RY6P2RY4P2RY14
SCHEMBL5068300 0.89 P2RY2 (0.63) P2RY2P2RY6P2RY4P2RY14ENPP1
SCHEMBL8440687 0.88 P2RY2 (0.62) P2RY2P2RY6P2RY4P2RY14ENPP1
SCHEMBL30612530 0.88 P2RY2 (0.62) P2RY2P2RY6P2RY4P2RY14ENPP1
SCHEMBL2167291 0.88 P2RY2 (0.62) P2RY2P2RY6P2RY4P2RY14ENPP1
SCHEMBL622267 0.87 P2RY2 (0.62) P2RY2P2RY6P2RY4P2RY14
SCHEMBL622268 0.87 P2RY2 (0.62) P2RY2P2RY6P2RY4P2RY14
SCHEMBL8440925 0.86 P2RY2 (0.60) P2RY2P2RY6P2RY4P2RY14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080150-A Mutant of L protein of rift valley fever virus and application thereof 2026-05-26 CN disclosed
WO-2026090505-A1 FLUOROPYRIMIDINE PARTICLES FOR THE TREATMENT OF CANCER WAKE FOREST UNIVERSITY HEALTH SCIENCES (US) 2026-04-30 WO disclosed
EP-3538151-B1 HUMAN PLASMA-LIKE MEDIUM WHITEHEAD INST BIOMEDICAL RES (US) 2024-06-26 EP disclosed
US-11993794-B2 Methods to create chemically-induced dimerizing protein systems for regulation of cellular events FRED HUTCHINSON CANCER CENTER (US) 2024-05-28 US disclosed
US-11925658-B2 Phosphoramidate derivatives of 5-fluoro-2′—deoxyuridine for use in the treatment of cancer NuCana plc (GB) 2024-03-12 US disclosed
CN-112679480-B Preparation method of tegafur 鲁南制药集团股份有限公司 2024-01-09 CN disclosed
CN-112759579-B Preparation method of antitumor drug tegafur 鲁南制药集团股份有限公司 2023-12-26 CN disclosed
CN-116850278-A RNA adjuvant capable of controllably loading therapeutic nucleoside analogues and preparation method and application thereof 上海交通大学 2023-10-10 CN disclosed
CN-116270509-A Orally disintegrating preparation containing tegafur, gimeracil and octreotide potassium 郑州大学第一附属医院 2023-06-23 CN disclosed
US-20230165886-A1 PHOSPHORAMIDATE DERIVATIVES OF 5 - FLUORO - 2' - DEOXYURIDINE FOR USE IN THE TREATMENT OF CANCER NuCana plc (GB) 2023-06-01 US disclosed
WO-2005046516-A2 MEDICAL IMPLANTS AND ANTI-SCARRING AGENTS ANGIOTECH INTERNATIONAL AG (CH) 2005-05-26 WO disclosed
WO-2005046746-A2 MEDICAL IMPLANTS AND FIBROSIS-INDUCING AGENTS ANGIOTECH INTERNATIONAL AG (CH) 2005-05-26 WO disclosed
WO-2005044142-A2 INTRAVASCULAR DEVICES AND FIBROSIS-INDUCING AGENTS ANGIOTECH INTERNATIONAL AG (CH) 2005-05-19 WO disclosed
US-20040265368-A1 Combination compositions of camptothecins and fluoropyrimidines CELATOR PHARMACEUTICALS, INC. 2004-12-30 US disclosed
WO-2004087115-A2 COMBINATION COMPOSITIONS OF CAMPTOTHECINS AND FLUOROPYRIMIDINES CELATOR PHARMACEUTICALS, INC. (US) 2004-10-14 WO disclosed
WO-2004087105-A1 COMBINATION FORMULATIONS OF PLATINUM AGENTS AND FLUOROPYRIMIDINES CELATOR PHARMACEUTICALS, INC. (US) 2004-10-14 WO disclosed
EP-0561303-B1 Conjugates of phenylalanine-glycine with antitumor substances KUREHA CHEMICAL IND CO LTD (JP) 1997-02-26 EP disclosed
US-5470960-A Antitumor agents KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1995-11-28 US disclosed
US-5411964-A Phenylalanine-glycine compounds having anti-tumor activity, process for preparation thereof, and pharmaceutical composition containing said compounds KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1995-05-02 US disclosed
EP-0561303-A2 Conjugates of phenylalanine-glycine with antitumor substances KUREHA CHEMICAL INDUSTRY CO., LTD. (JP) 1993-09-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230165886-A1 PHOSPHORAMIDATE DERIVATIVES OF 5 - FLUORO - 2' - DEOXYURIDINE FOR USE IN THE TREATMENT OF CANCER SLC29A2, SLC29A1, TYMP P2RY2 773/4885P2RY6 795/4885P2RY4 1067/4885
US-11925658-B2 Phosphoramidate derivatives of 5-fluoro-2′—deoxyuridine for use in the treatment of cancer SLC29A2, SLC29A1, TYMP P2RY2 717/4885P2RY6 744/4885P2RY4 1000/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.