⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10626556 | 0.83 | TSHR (0.36) | — | |
| SCHEMBL258549 | 0.82 | TSHR (0.32) | — | |
| SCHEMBL365630 | 0.81 | HEXA (0.36) | — | |
| SCHEMBL28133189 | 0.79 | — | — | |
| SCHEMBL18705898 | 0.79 | — | — | |
| SCHEMBL18705643 | 0.79 | — | — | |
| SCHEMBL27954141 | 0.79 | — | — | |
| SCHEMBL819968 | 0.79 | SKP2 (0.35) | — | |
| SCHEMBL8974022 | 0.78 | CNR1 (0.34) | — | |
| SCHEMBL7668652 | 0.78 | TAAR1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1345 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116410239-A | Heteroatom-containing metallocene compound and preparation method and application thereof | 惠生(中国)投资有限公司 | 2023-07-11 | — | — | CN | claimed |
| CN-115785083-A | Cathepsin C small-molecule inhibitor and preparation method thereof | 瑞石生物医药有限公司 | 2023-03-14 | — | — | CN | claimed |
| CN-110818545-B | Method for preparing substituted aryl ketone by ketone arylation | 上海化工研究院有限公司 | 2022-12-09 | — | — | CN | claimed |
| CN-110922286-B | Asymmetric aryl substituted fulvene compound and preparation method and application thereof | 上海化工研究院有限公司 | 2022-08-16 | — | — | CN | claimed |
| CN-112920199-A | Piperazinone substituent or derivative thereof, and preparation method, application and pharmaceutical composition thereof | 四川大学 | 2021-06-08 | — | — | CN | claimed |
| EP-2455426-B1 | POLYCARBONATE RESIN COMPOSITION HAVING HIGH GLOSS AND IMPACT RESISTANCE AND GOOD SURFACE PROPERTIES, AND MOLDED ARTICLE USING THE SAME | LOTTE ADVANCED MAT CO LTD (KR) | 2021-01-06 | — | — | EP | claimed |
| CN-108164646-B | Method for preparing polyisoprene by steam cracking of C5 naphtha fraction | 中国石油化工股份有限公司 | 2020-09-15 | — | — | CN | claimed |
| CN-106349217-B | Serine/threonine kinase inhibitors | 阵列生物制药公司 | 2020-08-28 | — | — | CN | claimed |
| CN-108192002-B | Method for preparing polyisoprene | 中国石油化工股份有限公司 | 2020-07-24 | — | — | CN | claimed |
| CN-110922286-A | Asymmetric aryl substituted fulvene compound and preparation method and application thereof | 上海化工研究院有限公司 | 2020-03-27 | — | — | CN | claimed |
| WO-2001049689-A2 | NOVEL SUBSTITUTED PYRAZOLO[4,3-e]DIAZEPINES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, USE AS MEDICINAL PRODUCTS AND PROCESSES FOR PREPARING THEM | WARNER-LAMBERT COMPANY (US) | 2001-07-12 | — | — | WO | claimed |
| US-6221989-B1 | CRESOL-FORMALDEHYDE RESIN CONTAINING TRIAZINE GROUPS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2001-04-24 | — | — | US | claimed |
| US-5952529-A | CATALYTIC AMINATION OF ALKANE OR ARYLALKANE DERIVATIVES COMPRISES CONTACTING ALKANE OR ARYLALKANE DERIVATIVES WITH AMMONIA OR REACTANT AMINE IN PRESENCE OF HYDROGEN AND NICKEL-RHENIUM-COBALT-BORON-COPPER OR RUTHENIUM CATALYST | THE DOW CHEMICAL COMPANY (US) | 1999-09-14 | — | — | US | claimed |
| US-5789490-A | Amine capped polyethers and process for producing same | THE DOW CHEMICAL COMPANY (US) | 1998-08-04 | — | — | US | claimed |
| EP-0853641-A1 | AMINE CAPPED POLYETHERS AND PROCESS FOR PRODUCING SAME | THE DOW CHEMICAL COMPANY (US) | 1998-07-22 | — | — | EP | claimed |
| EP-0828558-A1 | CATALYST AND PROCESS FOR PRODUCING AMINES | THE DOW CHEMICAL COMPANY (US) | 1998-03-18 | — | — | EP | claimed |
| WO-1997012928-A1 | AMINE CAPPED POLYETHERS AND PROCESS FOR PRODUCING SAME | THE DOW CHEMICAL COMPANY (US) | 1997-04-10 | — | — | WO | claimed |
| WO-1996038226-A1 | CATALYST AND PROCESS FOR PRODUCING AMINES | THE DOW CHEMICAL COMPANY (US) | 1996-12-05 | — | — | WO | claimed |
| US-4797347-A | Process for producing electrically conductive coating | CIBA-GEIGY CORPORATION (US) | 1989-01-10 | — | — | US | claimed |
| US-4626556-A | LADDER POLYMERS | JAPAN SYNTHETIC RUBBER CO., LTD. (JP) | 1986-12-02 | — | — | US | claimed |