SCHEMBL258549

SCHEMBL258549

CCCc1[c]cccc1C

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.32
ACHE P22303 1/20 0.32
TAAR1 Q96RJ0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL819968 0.88 SKP2 (0.35)
SCHEMBL815744 0.86 KCNH2 (0.40) ACHE
SCHEMBL980143 0.84 KCNH2 (0.43) ACHE
SCHEMBL984975 0.84 KCNH2 (0.43) ACHE
SCHEMBL983090 0.84 KCNH2 (0.43) ACHE
SCHEMBL2958748 0.84 KCNH2 (0.43) ACHE
SCHEMBL3223563 0.84 KCNH2 (0.43) ACHE
SCHEMBL815610 0.84 KCNH2 (0.43) ACHE
SCHEMBL984972 0.84 KCNH2 (0.43) ACHE
SCHEMBL982033 0.84 KCNH2 (0.43) ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 256 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116410239-A Heteroatom-containing metallocene compound and preparation method and application thereof 惠生(中国)投资有限公司 2023-07-11 CN claimed
CN-110818545-B Method for preparing substituted aryl ketone by ketone arylation 上海化工研究院有限公司 2022-12-09 CN claimed
CN-110922286-B Asymmetric aryl substituted fulvene compound and preparation method and application thereof 上海化工研究院有限公司 2022-08-16 CN claimed
CN-110922286-A Asymmetric aryl substituted fulvene compound and preparation method and application thereof 上海化工研究院有限公司 2020-03-27 CN claimed
CN-110818545-A Method for preparing substituted aryl ketone by ketone arylation 上海化工研究院有限公司 2020-02-21 CN claimed
CN-106083925-B Diphosphonic acid compound and preparation method and application thereof 成都云克药业有限责任公司 2019-12-31 CN claimed
US-7247687-B2 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-07-24 US claimed
EP-1521758-B1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEM PATENTS INC (US) 2006-05-24 EP claimed
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization EXXONMOBIL CHEMICAL PATENTS INC. 2006-03-02 US claimed
EP-1521758-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION Exxonmobil Chemical Patents Inc. (US) 2005-04-13 EP claimed
WO-2004007509-A1 LATE TRANSITION METAL CATALYSTS FOR OLEFIN POLYMERIZATION AND OLIGOMERIZATION EXXONMOBIL CHEMICAL PATENTS INC. (US) 2004-01-22 WO claimed
US-4626556-A LADDER POLYMERS JAPAN SYNTHETIC RUBBER CO., LTD. (JP) 1986-12-02 US claimed
CN-112279864-B Difunctional coumarin oxime ester compound and preparation and application thereof 湖北固润科技股份有限公司 2024-07-16 CN disclosed
CN-118302407-A Carbonyl compound, method for producing isocyanate compound, and isocyanate composition 旭化成株式会社 2024-07-05 CN disclosed
CN-118215651-A Method for producing isocyanate compound, method for producing urethane compound, method for recovering amine compound, and isocyanate composition 旭化成株式会社 2024-06-18 CN disclosed
CN-117865922-A Formylcarboxylate coumarin compounds, methods of preparation and use thereof, and photoinitiator compositions containing same 湖北固润科技股份有限公司 2024-04-12 CN disclosed
EP-0025017-A1 Polyazathia compounds, process for their preparation, pharmaceutical preparations containing such compounds and use of the latter CIBA-GEIGY AG (CH) 1981-03-11 EP disclosed
EP-0016296-A1 Cephalosporin derivatives, process for their preparation, compositions containing them, and intermediates and their preparation CIBA-GEIGY AG (CH) 1980-10-01 EP disclosed
US-4089955-A ANTIBIOTICS CIBA-GEIGY CORPORATION (US) 1978-05-16 US disclosed
US-4069324-A CEPHALOSPORIN ANTIBIOTICS CIBA-GEIGY CORPORATION (US) 1978-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060047094-A1 Late transition metal catalysts for olefin polymerization and oligomerization MLX, LOX, LMTK3 TSHR 4680/4885ACHE 3995/4885TAAR1 2284/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.