Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 8/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.65 |
| ▸ | ATM | Q13315 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.49 |
| ▸ | PSMB2 | P49721 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR7 | P34969 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.48 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.48 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL229697 | 0.83 | LTA4H (0.90) | LTA4HPTGS2ATML3MBTL1TSHR | |
| SCHEMBL31326956 | 0.82 | KCNA5 (0.60) | LTA4HKCNA5HTR1A | |
| SCHEMBL5116881 | 0.82 | LTA4H (0.87) | LTA4HPTGS2ATML3MBTL1TSHR | |
| SCHEMBL227976 | 0.82 | LTA4H (0.87) | LTA4HPTGS2ATML3MBTL1KDM4E | |
| SCHEMBL227425 | 0.82 | LTA4H (0.87) | LTA4HPTGS2ATML3MBTL1KDM4E | |
| SCHEMBL30286346 | 0.81 | DRD3 (0.63) | LTA4HKCNA5 | |
| SCHEMBL5117118 | 0.81 | LTA4H (0.84) | LTA4HPTGS2ATML3MBTL1KDM4E | |
| SCHEMBL5139685 | 0.81 | LTA4H (0.84) | LTA4HPTGS2ATML3MBTL1KDM4E | |
| SCHEMBL18824538 | 0.79 | ATM (0.81) | LTA4HPTGS2ATML3MBTL1TSHR | |
| SCHEMBL21674339 | 0.78 | KDM4E (0.54) | LTA4HPTGS2ATML3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3082805-B1 | SUBSTITUTED AMINO TRIAZOLES, AND METHODS USING SAME | INST FOR DRUG DISCOVERY LLC (US) | 2020-02-05 | — | — | EP | disclosed |