Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.74 |
| ▸ | MEN1 | O00255 | 4/20 | 0.74 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.62 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | CA1 | P00915 | 3/20 | 0.55 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5383057 | 0.93 | KMT2A (0.76) | KMT2AMEN1SLC6A2SLC6A3TDP1 | |
| SCHEMBL20679817 | 0.91 | KMT2A (0.69) | KMT2AMEN1SLC6A2SLC6A3TDP1 | |
| SCHEMBL6156961 | 0.85 | KMT2A (0.65) | KMT2AMEN1SLC6A2SLC6A3TDP1 | |
| SCHEMBL29245494 | 0.85 | KMT2A (1.00) | KMT2AMEN1SLC6A2SLC6A3TDP1 | |
| SCHEMBL1549061 | 0.85 | KMT2A (1.00) | KMT2AMEN1SLC6A2SLC6A3TDP1 | |
| SCHEMBL4443427 | 0.84 | CA1 (0.63) | KMT2AMEN1TDP1LMNAALDH1A1 | |
| SCHEMBL3254724 | 0.84 | CA1 (0.63) | KMT2AMEN1TDP1LMNAALDH1A1 | |
| SCHEMBL7971504 | 0.84 | KMT2A (0.53) | KMT2AMEN1SLC6A2SLC6A3TDP1 | |
| SCHEMBL13873955 | 0.84 | KMT2A (0.53) | KMT2AMEN1SLC6A2SLC6A3TDP1 | |
| SCHEMBL11703832 | 0.83 | KMT2A (0.74) | KMT2AMEN1SLC6A2SLC6A3TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11198761-B2 | Biodegradable polyionenes | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2021-12-14 | — | — | US | disclosed |
| US-20200040136-A1 | BIODEGRADABLE POLYIONENES | AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH (SG) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200040136-A1 | BIODEGRADABLE POLYIONENES | DCLRE1A, PLD2, CCNA2 | KMT2A 2633/4885MEN1 1685/4885SLC6A2 4395/4885 |
| US-11198761-B2 | Biodegradable polyionenes | DCLRE1A, PLD2, CCNA2 | KMT2A 2633/4885MEN1 1685/4885SLC6A2 4395/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.