PLD2 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
Halopemide (SCHEMBL121267)	1.00	20/20
SCHEMBL794432	0.46	18/20
SCHEMBL795275	0.47	17/20
SCHEMBL787981	0.47	17/20
SCHEMBL793910	0.53	16/20
SCHEMBL788578	0.46	16/20
SCHEMBL794661	0.46	16/20
SCHEMBL806210	0.44	16/20
SCHEMBL795392	0.46	15/20
SCHEMBL806218	0.46	15/20
SCHEMBL798698	0.45	15/20
SCHEMBL798699	0.45	15/20
SCHEMBL788137	0.44	15/20
SCHEMBL788134	0.44	15/20
SCHEMBL793278	0.43	15/20
SCHEMBL788336	0.37	15/20
SCHEMBL798610	0.49	14/20
SCHEMBL794584	0.49	14/20
SCHEMBL798569	0.49	14/20
SCHEMBL793985	0.48	14/20

Clinical trials — most relevant to PLD2 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
A Randomized Controlled Pilot Trial of Indomethacin in Acute Pancreatitis	PHASE3	COMPLETED
Sequential Therapy With Tacrolimus and Rituximab in Primary Membranous Nephropathy	PHASE3	COMPLETED
Ramatroban/Montelukast Versus Montelukast/Placebo on the Early Allergic Reaction in Asthma Sensitive to House Dust Mite	PHASE2/PHASE3	WITHDRAWN
Aspirin and Renal Disease Progression in Patients With Type 2 Diabetes	PHASE3	UNKNOWN
Lovaza's Effect on the Activation of Platelets	PHASE2	COMPLETED
IN10018 in Combination With Pegylated Liposomal Doxorubicin (PLD) vs. Placebo in Combination With PLD for the Treatment of Platinum-resistant Recurrent Ovarian Cancer	PHASE2	RECRUITING
Ibuprofen Versus Acetaminophen for Treatment of Mild Traumatic Brain Injury	PHASE2	WITHDRAWN
Effect of Gemfibrozil on Serum Glycosylphosphatidylinositol (GPI) Phospholipase D and Triglycerides	PHASE1	COMPLETED
A Positional Cloning Study on Schizophrenia	nan	COMPLETED
PET Imaging of DHA Metabolism	nan	COMPLETED
Effects of Probiotics on Gut Microbiota, Endocannabinoid and Immune Activation and Symptoms of Fatigue in Dancers	nan	COMPLETED
Gene Expression of Endocannabinoid System in Episodic and Chronic Migraine Patients	nan	COMPLETED
Mucomyst for Hepatitis C	nan	SUSPENDED
Plasma Free Fatty Acids Profile As A Diagnostic Tool For Acute Ischemic Stroke	nan	COMPLETED
Supplemental Choline and Brain Development in Humans	nan	COMPLETED
EPICO: (Study for the Pro-resolution of Chronic Inflammation in Obesity. Original Acronym From Spanish)	nan	UNKNOWN
Molecular Genetic Study of Schizophrenia: Parent-Offspring Trios	nan	COMPLETED
Duality of Lipids: the Athlete's Paradox	nan	COMPLETED
Positron Emission Tomography (PET) to Study Brain Signaling	nan	COMPLETED
The Role of Programmed Death Ligand -1 (Pdl-1) in Lung Cancer	nan	COMPLETED
Autotaxin (ATX) as a Marker for Breast Cancer	nan	UNKNOWN
Skeletal Muscle Diacylglycerol and Sphingolipids - Impact of Localization and Species on Insulin Resistance in Humans	nan	COMPLETED
Candida Associated Cytokines in Oral Leukoplakia	nan	COMPLETED
The Role of Arachidonic Acid Metabolites, From Patients With Metabolic Syndrome	nan	UNKNOWN
Relation Between Prostaglandin E2 Metabolite Levels and the Development of Hemodynamically Significant Patent Ductus Arteriosus in Preterm Neonates	nan	RECRUITING
Maresin-1 and Resolvin-D1 Levels and Disease Activity in Ulcerative Colitis	nan	COMPLETED
Weathering the Storm: Lung, Heart, and Brain Vascular Rehabilitation for COVID-19	nan	UNKNOWN
Avocado Consumption, Nutrients in Human Milk, and Infant Cognitive Development	nan	RECRUITING
Investigating the Genetic Basis of Pseudoexfoliation Syndrome, Angle-closure Glaucoma and Primary Open-angle Glaucoma	nan	RECRUITING
Dietary Intake of Whole Walnuts in Adult Subjects Under Low Cardiovascular Risk	nan	COMPLETED

Related proteins — ESM-2 sequence neighbours (a PLD2 binder may also engage these)

Protein	Name	Similarity
Q0V8L6	—	1.000	Q0V8L6 →
P97813	—	1.000	P97813 →
P70498	—	1.000	P70498 →
O08684	—	0.989	O08684 →
P70496	—	0.987	P70496 →
Q9M9W8	—	0.986	Q9M9W8 →
Q9Z280	—	0.986	Q9Z280 →
O82549	—	0.985	O82549 →
Q9C5Y0	—	0.983	Q9C5Y0 →
PLD1	Phospholipase D1	0.983	landscape →
Q9T051	—	0.982	Q9T051 →
Q5FVH2	—	0.981	Q5FVH2 →
Q43007	—	0.981	Q43007 →
O23078	—	0.981	O23078 →
PLD3	5'-3' exonuclease PLD3	0.980	landscape →
Q9SSQ9	—	0.980	Q9SSQ9 →
Q9LRZ5	—	0.980	Q9LRZ5 →
P93844	—	0.980	P93844 →
Q41142	—	0.978	Q41142 →
Q38882	—	0.978	Q38882 →
Q43270	—	0.978	Q43270 →
Q9T052	—	0.978	Q9T052 →
P42348	—	0.977	P42348 →
Q8R3B1	—	0.976	Q8R3B1 →
Q4R583	—	0.976	Q4R583 →
Q8BG07	—	0.975	Q8BG07 →
O04865	—	0.975	O04865 →
PLCD1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-1	0.975	landscape →
Q5R4Y7	—	0.975	Q5R4Y7 →
O02697	—	0.975	O02697 →