Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | BCHE | P06276 | 1/20 | 0.36 |
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.34 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ACACA | Q13085 | 1/20 | 0.33 |
| ▸ | NQO2 | P16083 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2797442 | 0.82 | EPHX1 (0.36) | EPHX1BCHEGPR88MEN1GAA | |
| SCHEMBL2166671 | 0.79 | EPHX1 (0.39) | EPHX1BCHENQO2 | |
| SCHEMBL27836334 | 0.78 | EPHX1 (0.41) | EPHX1BCHEIDO1UTS2RGPR88 | |
| SCHEMBL2167444 | 0.78 | EPHX1 (0.36) | EPHX1BCHEIDO1GPR88NQO2 | |
| SCHEMBL2178099 | 0.76 | IDO1 (0.42) | IDO1MEN1KMT2ABACE1 | |
| SCHEMBL2173930 | 0.75 | MALT1 (0.36) | IDO1UTS2RMEN1GAAKMT2A | |
| SCHEMBL2177713 | 0.75 | BACE1 (0.44) | IDO1MEN1KMT2ABACE1 | |
| SCHEMBL3124904 | 0.74 | CYP3A4 (0.38) | EPHX1MEN1GAAKMT2ANQO2 | |
| SCHEMBL2821039 | 0.74 | GPR88 (0.39) | IDO1GPR88MEN1GAAKMT2A | |
| SCHEMBL2167622 | 0.74 | USP30 (0.36) | USP30IDO1UTS2RGPR88CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2340242-A2 | COMPOUNDS FOR TREATING OPHTHALMIC DISEASES AND DISORDERS | Acucela, Inc. (US) | 2011-07-06 | — | — | EP | disclosed |