SCHEMBL2167455

SCHEMBL2167455

CCCOC(=O)C1C(/C=C(/C)C=O)C1(C)C

nearest known ligand 0.56

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.56
TSHR P16473 2/20 0.41
TDP1 Q9NUW8 3/20 0.37
CYP1A2 P05177 2/20 0.37
CYP2C19 P33261 2/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
CYP2C9 P11712 1/20 0.37
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
ADRA2A P08913 1/20 0.34
CNR1 P21554 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
PPM1B O75688 1/20 0.31
PTPN1 P18031 1/20 0.31
PPP1CC P36873 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2167462 1.00 LMNA (0.56) LMNATSHRTDP1CYP1A2CYP2C19
SCHEMBL2167460 1.00 LMNA (0.56) LMNATSHRTDP1CYP1A2CYP2C19
SCHEMBL3677167 0.91 LMNA (0.54) LMNATSHRTDP1CYP1A2CYP2C19
SCHEMBL3677170 0.91 LMNA (0.54) LMNATSHRTDP1CYP1A2CYP2C19
SCHEMBL2167961 0.88 LMNA (0.73) LMNATSHRTDP1CYP1A2CYP2C19
SCHEMBL1072841 0.88 LMNA (0.73) LMNATSHRTDP1CYP1A2CYP2C19
SCHEMBL1072844 0.88 LMNA (0.73) LMNATSHRTDP1CYP1A2CYP2C19
SCHEMBL296159 0.86 LMNA (0.76) LMNATSHRTDP1CYP1A2CYP2C19
SCHEMBL294548 0.83 LMNA (0.57) LMNATSHRTDP1CYP1A2CYP2C19
SCHEMBL3678627 0.82 LMNA (0.54) LMNATSHRTDP1CYP1A2CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1970368-B1 METHOD FOR PRODUCING OLEFIN COMPOUND SUMITOMO CHEMICAL CO (JP) 2012-08-29 EP disclosed
US-7985872-B2 Method for producing olefin compound SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2011-07-26 US disclosed
US-20090036620-A1 METHOD FOR PRODUCING OLEFIN COMPOUND SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2009-02-05 US disclosed
EP-1970368-A1 METHOD FOR PRODUCING OLEFIN COMPOUND Sumitomo Chemical Company, Limited (JP) 2008-09-17 EP disclosed