Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 17/20 | 0.46 |
| ▸ | CREBBP | Q92793 | 9/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | IDH1 | O75874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17018283 | 0.89 | BRD4 (0.46) | BRD4CREBBPGSK3BDYRK1A | |
| SCHEMBL17018282 | 0.89 | BRD4 (0.46) | BRD4CREBBPGSK3BDYRK1A | |
| SCHEMBL21249959 | 0.87 | BRD4 (0.47) | BRD4CREBBPGSK3BDYRK1A | |
| SCHEMBL17018120 | 0.86 | BRD4 (0.51) | BRD4CREBBPGSK3BDYRK1ANAMPT | |
| SCHEMBL23733972 | 0.85 | BRD4 (0.42) | BRD4CREBBPIDH1 | |
| SCHEMBL17018259 | 0.84 | BRD4 (0.49) | BRD4GSK3BDYRK1ANAMPT | |
| SCHEMBL17018249 | 0.84 | BRD4 (0.49) | BRD4CREBBPGSK3BDYRK1A | |
| SCHEMBL17018118 | 0.84 | BRD4 (0.52) | BRD4CREBBPNAMPTIDH1 | |
| SCHEMBL16722066 | 0.83 | BRD4 (0.51) | BRD4CREBBPGSK3BDYRK1ANAMPT | |
| SCHEMBL17018117 | 0.82 | BRD4 (0.51) | BRD4NAMPTIDH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071205-B1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | FORMA THERAPEUTICS INC (US) | 2020-02-05 | — | — | EP | disclosed |