Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 14/20 | 0.42 |
| ▸ | CREBBP | Q92793 | 7/20 | 0.33 |
| ▸ | IDH1 | O75874 | 1/20 | 0.31 |
| ▸ | TTK | P33981 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21674830 | 0.85 | BRD4 (0.46) | BRD4CREBBPIDH1 | |
| SCHEMBL17018249 | 0.82 | BRD4 (0.49) | BRD4CREBBPTTK | |
| SCHEMBL17018120 | 0.81 | BRD4 (0.51) | BRD4CREBBPTTK | |
| SCHEMBL17018282 | 0.81 | BRD4 (0.46) | BRD4CREBBP | |
| SCHEMBL17018283 | 0.81 | BRD4 (0.46) | BRD4CREBBP | |
| SCHEMBL21249959 | 0.81 | BRD4 (0.47) | BRD4CREBBP | |
| SCHEMBL17018259 | 0.80 | BRD4 (0.49) | BRD4TTK | |
| SCHEMBL17018118 | 0.80 | BRD4 (0.52) | BRD4CREBBPIDH1 | |
| SCHEMBL16722066 | 0.79 | BRD4 (0.51) | BRD4CREBBPIDH1 | |
| SCHEMBL17018258 | 0.79 | BRD4 (0.47) | BRD4CREBBPTTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11084831-B1 | Benzopiperazine compositions as BET bromodomain inhibitors | FORMA THERAPEUTICS, INC. (US) | 2021-08-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11084831-B1 | Benzopiperazine compositions as BET bromodomain inhibitors | BRD4, BRPF3, BRD7 | BRD4 1/4885CREBBP 28/4885IDH1 1674/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.