Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 15/20 | 0.69 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16721508 | 1.00 | BRD4 (0.69) | BRD4TSHRNPC1 | |
| SCHEMBL16722086 | 0.96 | BRD4 (0.74) | BRD4NPC1 | |
| SCHEMBL21675110 | 0.92 | BRD4 (0.69) | BRD4TSHR | |
| SCHEMBL16721451 | 0.92 | BRD4 (0.69) | BRD4TSHR | |
| SCHEMBL16722618 | 0.88 | BRD4 (0.74) | BRD4NPC1 | |
| SCHEMBL21675353 | 0.88 | BRD4 (0.74) | BRD4NPC1 | |
| SCHEMBL21674893 | 0.87 | BRD4 (0.67) | BRD4NPC1 | |
| SCHEMBL16722085 | 0.87 | BRD4 (0.67) | BRD4NPC1 | |
| SCHEMBL16721234 | 0.87 | BRD4 (0.58) | BRD4 | |
| SCHEMBL16721411 | 0.87 | BRD4 (0.64) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071205-B1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | FORMA THERAPEUTICS INC (US) | 2020-02-05 | — | — | EP | disclosed |