Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 16/20 | 0.74 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | BRD2 | P25440 | 1/20 | 0.35 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16722618 | 1.00 | BRD4 (0.74) | BRD4NR1H2NR1H3NPC1BRD2 | |
| SCHEMBL16721451 | 0.96 | BRD4 (0.69) | BRD4 | |
| SCHEMBL21675110 | 0.96 | BRD4 (0.69) | BRD4 | |
| SCHEMBL16722086 | 0.92 | BRD4 (0.74) | BRD4NPC1 | |
| SCHEMBL21532330 | 0.90 | BRD4 (0.66) | BRD4NPC1 | |
| SCHEMBL16721157 | 0.89 | BRD4 (0.58) | BRD4BRD2BRD3 | |
| SCHEMBL16721508 | 0.88 | BRD4 (0.69) | BRD4NPC1 | |
| SCHEMBL21675294 | 0.88 | BRD4 (0.69) | BRD4NPC1 | |
| SCHEMBL21532082 | 0.87 | BRD4 (0.61) | BRD4 | |
| SCHEMBL16722480 | 0.85 | BRD4 (1.00) | BRD4NPC1BRD2BRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3071205-B1 | BENZOPIPERAZINE COMPOSITIONS AS BET BROMODOMAIN INHIBITORS | FORMA THERAPEUTICS INC (US) | 2020-02-05 | — | — | EP | disclosed |