Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | ACACB | O00763 | 5/20 | 0.34 |
| ▸ | ACACA | Q13085 | 5/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23507770 | 0.93 | ELANE (0.40) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL19157467 | 0.89 | ELANE (0.38) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL20259448 | 0.87 | POLB (0.43) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL18500369 | 0.86 | THRB (0.35) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL26142434 | 0.86 | POLB (0.35) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL23350668 | 0.85 | APP (0.42) | KMT2ATSHRPTGS2HIF1A | |
| SCHEMBL18808279 | 0.85 | ELANE (0.34) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL19158301 | 0.84 | ELANE (0.38) | ELANEPOLBAPEX1HTTTDP1 | |
| SCHEMBL19157792 | 0.83 | FFAR1 (0.38) | POLBAPEX1HTTTDP1THRB | |
| SCHEMBL18806033 | 0.83 | ELANE (0.39) | ELANEPOLBAPEX1HTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220220383-A1 | METHOD FOR PREPARING A LIQUID CRYSTAL-BASED SWITCHING ELEMENT | MERCK PATENT GMBH (DE) | 2022-07-14 | — | — | US | disclosed |
| US-20200040257-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2020-02-06 | — | — | US | disclosed |