SCHEMBL216757

SCHEMBL216757

CCCCC=C[SiH](C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5968580 1.00
Water SCHEMBL27852585 0.97 TSHR (0.38)
SCHEMBL16209866 0.90 FAAH (0.50)
SCHEMBL10824857 0.90 FAAH (0.50)
SCHEMBL296578 0.90 FAAH (0.50)
SCHEMBL16209865 0.90 FAAH (0.50)
SCHEMBL296579 0.90 FAAH (0.50)
SCHEMBL8992206 0.83 TSHR (0.39)
SCHEMBL3391290 0.82
SCHEMBL8992283 0.80 TSHR (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024129419-A1 THERMOPLASTIC POLYOLEFIN COMPOSITION WITH REACTIVE COMPATIBILIZATION DOW GLOBAL TECHNOLOGIES, LLC (US) 2024-06-20 WO claimed
CN-111333411-A Wear-resistant part and ceramic wear-resistant material used by same 衢州东方特钢有限公司 2020-06-26 CN claimed
CN-100374525-C Solventless silicone pressure sensitive adhesives with improved high temperature cohesive strength DOW CORNING (US) 2008-03-12 CN claimed
EP-1259556-B1 IMPROVED DERIVATIVES OF SILANE FUNCTIONALIZED OLEFIN INTERPOLYMERS DOW GLOBAL TECHNOLOGIES INC (US) 2006-06-07 EP claimed
CN-1756822-A Solventless silicone pressure sensitive adhesives with improved high temperature cohesive strength DOW CORNING (US) 2006-04-05 CN claimed
CN-1229423-C Process for the condensution of compounds having silicon bonded hydroxy or alkoxy groups DOW CORNING (US) 2005-11-30 CN claimed
CN-1656174-A Composition for bath life improvement DOW CORNING (US) 2005-08-17 CN claimed
US-5516871-A Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof DOW CORNING ASIA, LTD. (JP) 1996-05-14 US claimed
US-5502229-A ENDCAPPING DOW CORNING ASIA, LTD. (JP) 1996-03-26 US claimed
EP-4519328-B1 PROCESS FOR MELT FUNCTIONALIZATION OF SILICON HYDRIDE CONTAINING POLYOLEFIN AND PRODUCT DOW GLOBAL TECHNOLOGIES LLC (US) 2026-03-04 EP disclosed
US-20250346689-A1 PROCESS FOR MELT FUNCTIONALIZATION OF SILICON HYDRIDE CONTAINING POLYOLEFIN AND PRODUCT DOW GLOBAL TECHNOLOGIES LLC (US) 2025-11-13 US disclosed
US-20250340680-A1 CO-AGENT ASSISTED FORMATION OF CROSSLINKED SILICON-POLYOLEFIN INTERPOLYMER UTILIZING CROSSLINK AGENT DOW GLOBAL TECHNOLOGIES LLC (US) 2025-11-06 US disclosed
US-12384861-B2 Crosslinked compositions from olefin/silane interpolymers DOW GLOBAL TECHNOLOGIES LLC (US) 2025-08-12 US disclosed
WO-2025072684-A9 SILANOL FUNCTIONAL POLYOLEFINS DOW GLOBAL TECHNOLOGIES LLC (US) 2025-06-19 WO disclosed
WO-2001009207-A2 IMPROVED SILANE FUNCTIONALIZED OLEFIN INTERPOLYMERS AND DERIVATIVES THEREOF THE DOW CHEMICAL COMPANY (US) 2001-02-08 WO disclosed
US-6087461-A SILANE COMPOUNDS AND ENDBLOCKING POLYMERS DOW CORNING LIMITED (GB) 2000-07-11 US disclosed
EP-0887358-A1 Process for making silyl endblocked organic polymers DOW CORNING LIMITED (GB) 1998-12-30 EP disclosed
US-5629273-A HYDRAULIC FLUIDS, COMPRESSOR FLUIDS, LUBRICANTS, SYNERGISTIC VISCOSITY REDUCTION DOW CORNING INCORPORATED (US) 1997-05-13 US disclosed
US-5516871-A Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof DOW CORNING ASIA, LTD. (JP) 1996-05-14 US disclosed
US-5502229-A ENDCAPPING DOW CORNING ASIA, LTD. (JP) 1996-03-26 US disclosed