Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 9/20 | 0.39 |
| ▸ | CTSK | P43235 | 8/20 | 0.39 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | CTSL | P07711 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.37 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.36 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21676541 | 0.84 | ATM (0.48) | ATMAAK1CTSSCTSKCTSB | |
| SCHEMBL18930774 | 0.81 | ATM (0.46) | ATMAAK1CTSSCTSKCTSB | |
| SCHEMBL18930601 | 0.80 | ATM (0.48) | ATMAAK1CTSSCTSKCTSB | |
| SCHEMBL18930760 | 0.79 | ATM (0.49) | ATMAAK1CTSSCTSKCTSB | |
| SCHEMBL21170221 | 0.77 | DRD2 (0.43) | ATMCTSSCTSKCTSBCTSL | |
| SCHEMBL18930771 | 0.77 | ATM (0.43) | ATMCTSSCTSKCTSBCTSL | |
| SCHEMBL18930490 | 0.76 | ATM (0.51) | ATMAAK1CTSSCTSKCTSB | |
| SCHEMBL2617251 | 0.76 | ATM (0.51) | ATMAAK1CTSSCTSKCTSB | |
| SCHEMBL21676601 | 0.76 | ATM (0.44) | ATMCTSSCTSKCTSBCTSL | |
| SCHEMBL18930494 | 0.76 | ATM (0.46) | ATMAAK1CTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3383865-B1 | FURANE DERIVATIVES AS INHIBITORS OF ATAD2 | Bayer Pharma AG (DE) | 2020-01-29 | — | — | EP | disclosed |