SCHEMBL21677964

SCHEMBL21677964

O=[N+]([O-])c1ccc(C2CC(F)CCO2)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC18A3 Q16572 1/20 0.38
ALDH1A1 P00352 3/20 0.36
LMNA P02545 2/20 0.36
POLB P06746 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36
EPHX1 P07099 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
HTR2A P28223 1/20 0.35
HTR2C P28335 1/20 0.35
HTR2B P41595 1/20 0.35
HRH3 Q9Y5N1 1/20 0.35
CRYZ Q08257 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA3 P07451 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23786499 1.00 SLC18A3 (0.38) SLC18A3ALDH1A1LMNAPOLBGAA
SCHEMBL28368682 0.87 SLC18A3 (0.45) SLC18A3ALDH1A1LMNAPOLBGAA
SCHEMBL28368681 0.87 SLC18A3 (0.45) SLC18A3ALDH1A1LMNAPOLBGAA
SCHEMBL28373802 0.87 SLC18A3 (0.45) SLC18A3ALDH1A1LMNAPOLBGAA
SCHEMBL27828507 0.79 KDM4E (0.47) SLC18A3ALDH1A1LMNAPOLBGAA
SCHEMBL27828506 0.79 KDM4E (0.47) SLC18A3ALDH1A1LMNAPOLBGAA
SCHEMBL20719816 0.76 SLC6A2 (0.40) HTR2CHTR2B
SCHEMBL1366108 0.75 SMN1; SMN2 (0.41) SLC18A3ALDH1A1POLBMAPTNAMPT
SCHEMBL21677966 0.75 TSHR (0.48) LMNAMEN1KMT2AHTR2CHTR2B
SCHEMBL1583098 0.75 TSHR (0.46) SLC18A3ALDH1A1LMNAPOLBGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2020023354-A1 CATALYSTS, METHODS OF MAKING, AND METHODS OF HYDROFLUORINATION UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. (US) 2020-01-30 WO disclosed