Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | CRYZ | Q08257 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28373802 | 1.00 | SLC18A3 (0.45) | SLC18A3LMNAMAPTPOLBGAA | |
| SCHEMBL28368681 | 1.00 | SLC18A3 (0.45) | SLC18A3LMNAMAPTPOLBGAA | |
| SCHEMBL27828507 | 0.91 | KDM4E (0.47) | SLC18A3LMNAMAPTPOLBGAA | |
| SCHEMBL27828506 | 0.91 | KDM4E (0.47) | SLC18A3LMNAMAPTPOLBGAA | |
| SCHEMBL23786499 | 0.87 | SLC18A3 (0.38) | SLC18A3LMNAMAPTPOLBGAA | |
| SCHEMBL21677964 | 0.87 | SLC18A3 (0.38) | SLC18A3LMNAMAPTPOLBGAA | |
| SCHEMBL1022578 | 0.86 | TSHR (0.46) | SLC18A3LMNAMAPTPOLBGAA | |
| SCHEMBL1583098 | 0.86 | TSHR (0.46) | SLC18A3LMNAMAPTPOLBGAA | |
| SCHEMBL1582559 | 0.86 | TSHR (0.46) | SLC18A3LMNAMAPTPOLBGAA | |
| Bicarbonate SCHEMBL27427069 | 0.85 | KDM4E (0.49) | SLC18A3MAPTALDH1A1KMT2ANAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111491930-A | Substituted indole compounds useful as T L R inhibitors | 百时美施贵宝公司 | 2020-08-04 | — | — | CN | disclosed |
| CN-105793430-B | Process for the preparation of chiral 2-arylmorpholines | 豪夫迈·罗氏有限公司 | 2020-03-03 | — | — | CN | disclosed |