Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21677920 | 1.00 | RNPEP (0.39) | RNPEPCYP2C9LMNAFOLH1ALDH1A1 | |
| SCHEMBL13233860 | 1.00 | RNPEP (0.39) | RNPEPCYP2C9LMNAFOLH1ALDH1A1 | |
| SCHEMBL24106596 | 0.85 | CYP2C9 (0.38) | RNPEPCYP2C9LMNAFOLH1ALDH1A1 | |
| SCHEMBL12766236 | 0.82 | LMNA (0.40) | RNPEPCYP2C9LMNAFOLH1ALDH1A1 | |
| SCHEMBL7606793 | 0.82 | LMNA (0.40) | RNPEPCYP2C9LMNAFOLH1ALDH1A1 | |
| SCHEMBL24377733 | 0.82 | LMNA (0.40) | RNPEPCYP2C9LMNAFOLH1ALDH1A1 | |
| SCHEMBL12537170 | 0.81 | CYP2C9 (0.40) | RNPEPCYP2C9LMNAFOLH1ALDH1A1 | |
| SCHEMBL16557399 | 0.81 | CYP2C9 (0.40) | RNPEPCYP2C9LMNAFOLH1ALDH1A1 | |
| SCHEMBL19487362 | 0.81 | LMNA (0.39) | RNPEPCYP2C9LMNAFOLH1ALDH1A1 | |
| SCHEMBL16557198 | 0.79 | FNTA (0.40) | RNPEPCYP2C9LMNAFOLH1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021159021-A1 | LIPID PRODRUGS OF NEUROSTEROIDS | PURETECH LYT, INC. (US) | 2021-08-12 | — | — | WO | disclosed |
| WO-2020028787-A1 | LIPID PRODRUGS OF PREGNANE NEUROSTEROIDS AND USES THEREOF | PureTech Health LLC (US) | 2020-02-06 | — | — | WO | disclosed |