Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 17/20 | 0.39 |
| ▸ | HSP90B1 | P14625 | 3/20 | 0.37 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.35 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30019616 | 1.00 | MET (0.49) | METCYP3A4CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL21644678 | 0.88 | MET (0.50) | METCYP3A4CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL21644569 | 0.86 | MET (0.68) | METCYP3A4CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL21678119 | 0.84 | MET (0.48) | METCYP3A4CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL30019516 | 0.84 | MET (0.48) | METCYP3A4CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL21644714 | 0.84 | MET (0.58) | METCYP3A4CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL30779610 | 0.80 | HSP90AA1 (0.41) | METCYP3A4CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL21644523 | 0.80 | HSP90AA1 (0.41) | METCYP3A4CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL21678120 | 0.77 | HSP90AA1 (0.39) | METCYP3A4CYP2C9CYP2B6CYP2C19 | |
| SCHEMBL30019603 | 0.77 | HSP90AA1 (0.39) | METCYP3A4CYP2C9CYP2B6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200039923-A1 | HEAT SHOCK PROTEIN 90 INHIBITORS | TAIPEI MEDICAL UNIVERSITY (TW) | 2020-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200039923-A1 | HEAT SHOCK PROTEIN 90 INHIBITORS | HSP90AB1, HSP90AB2P, HSP90AA1 | MET 887/4885CYP3A4 4066/4885CYP2C9 4003/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.