Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | PARP1 | P09874 | 1/20 | 0.51 |
| ▸ | MPO | P05164 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.41 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 3/20 | 0.40 |
| ▸ | MAPK9 | P45984 | 3/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL535668 | 0.85 | L3MBTL1 (0.58) | L3MBTL1PARP1MPOKDM4ECYP1A2 | |
| SCHEMBL28677368 | 0.83 | L3MBTL1 (0.57) | L3MBTL1PARP1MPOKDM4ECYP1A2 | |
| SCHEMBL1979301 | 0.82 | L3MBTL1 (0.55) | L3MBTL1PARP1MPOKDM4ECYP1A2 | |
| SCHEMBL18216628 | 0.82 | L3MBTL1 (0.55) | L3MBTL1PARP1MPOKDM4ECYP1A2 | |
| SCHEMBL28759101 | 0.82 | L3MBTL1 (0.55) | L3MBTL1PARP1MPOKDM4ECYP1A2 | |
| SCHEMBL25414723 | 0.82 | L3MBTL1 (0.55) | L3MBTL1PARP1MPOKDM4ECYP1A2 | |
| SCHEMBL128967 | 0.82 | L3MBTL1 (0.55) | L3MBTL1PARP1MPOKDM4ECYP1A2 | |
| SCHEMBL12948310 | 0.82 | L3MBTL1 (0.55) | L3MBTL1PARP1MPOKDM4ECYP1A2 | |
| SCHEMBL30980820 | 0.82 | KDM4E (0.44) | L3MBTL1PARP1KDM4ECYP1A2MAPT | |
| SCHEMBL30036150 | 0.82 | L3MBTL1 (0.55) | L3MBTL1PARP1MPOKDM4ECYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020022237-A1 | FUSED RING LACTAM DERIVATIVES | 大日本住友製薬株式会社 | 2020-01-30 | — | — | WO | disclosed |