Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170224 | 0.95 | KMT2A (0.41) | NPC1RAB9AKMT2AMAOBPKM | |
| SCHEMBL2167129 | 0.91 | KMT2A (0.41) | NPC1RAB9AKMT2AMAOBPKM | |
| SCHEMBL2169110 | 0.91 | KMT2A (0.44) | NPC1RAB9AKMT2AMAOBPKM | |
| SCHEMBL18887236 | 0.90 | GAA (0.36) | NPC1RAB9AKMT2AMAOBPKM | |
| SCHEMBL2169453 | 0.90 | NPC1 (0.40) | NPC1RAB9AKMT2AMAOBPKM | |
| SCHEMBL2170672 | 0.88 | KMT2A (0.41) | NPC1RAB9AKMT2AMAOBPKM | |
| SCHEMBL2167412 | 0.86 | MAPT (0.44) | NPC1RAB9AKMT2AMAOBPKM | |
| SCHEMBL2169102 | 0.86 | NPC1 (0.42) | NPC1RAB9AKMT2AMAOBPKM | |
| SCHEMBL18887410 | 0.86 | TSHR (0.39) | NPC1RAB9AKMT2AMAOBGAA | |
| SCHEMBL2168916 | 0.85 | KMT2A (0.42) | NPC1RAB9AKMT2AMAOBPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4732354-B2 | — | — | 2011-07-27 | — | — | JP | claimed |