Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPEP | Q07075 | 16/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SLC6A6 | P31641 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2167503 | 1.00 | ENPEP (0.42) | ENPEPTP53S1PR2S1PR1S1PR3 | |
| SCHEMBL2167506 | 1.00 | ENPEP (0.42) | ENPEPTP53S1PR2S1PR1S1PR3 | |
| SCHEMBL2168312 | 0.89 | ENPEP (0.40) | ENPEPTP53S1PR2S1PR1S1PR3 | |
| SCHEMBL7055144 | 0.87 | ENPEP (0.40) | ENPEPTP53S1PR2S1PR1S1PR3 | |
| SCHEMBL2168652 | 0.86 | ENPEP (0.43) | ENPEPTP53S1PR2S1PR1S1PR3 | |
| SCHEMBL2167512 | 0.86 | ENPEP (0.43) | ENPEPTP53S1PR2S1PR1S1PR3 | |
| SCHEMBL2168649 | 0.86 | ENPEP (0.43) | ENPEPTP53S1PR2S1PR1S1PR3 | |
| SCHEMBL3626027 | 0.79 | ENPEP (0.43) | ENPEPTP53S1PR2S1PR1S1PR3 | |
| SCHEMBL4744742 | 0.79 | S1PR2 (0.44) | ENPEPTP53S1PR2S1PR1S1PR3 | |
| SCHEMBL21623887 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4726304-B2 | — | — | 2011-07-20 | — | — | JP | claimed |
| JP-2003517458-A | — | — | 2003-05-27 | — | — | JP | claimed |
| EP-1276483-A2 | COMPOSITIONS AND METHODS FOR TREATING AMYLOIDOSIS USING SULPHONATE DERIVATIVES | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2003-01-22 | — | — | EP | claimed |
| WO-2000064420-A2 | COMPOSITIONS AND METHODS FOR TREATING AMYLOIDOSIS USING SULPHONATE DERIVATIVES | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2000-11-02 | — | — | WO | claimed |