Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.31 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.31 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.31 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Succinic Acid SCHEMBL22691726 | 0.93 | NPSR1 (0.39) | NPSR1TSHRKMT2AHTTMEN1 | |
| Phosphoric Acid SCHEMBL28041424 | 0.85 | — | — | |
| Phosphoric Acid SCHEMBL27817551 | 0.84 | — | — | |
| Glycolic Acid SCHEMBL19615736 | 0.82 | NOTUM (0.33) | NPSR1MCL1 | |
| Glycolic Acid SCHEMBL28396238 | 0.82 | NOTUM (0.33) | NPSR1MCL1 | |
| Phosphoric Acid SCHEMBL6864987 | 0.78 | — | — | |
| SCHEMBL3266306 | 0.77 | NOTUM (0.35) | TSHRMCL1MAPK1 | |
| SCHEMBL152676 | 0.74 | — | — | |
| Citric Acid SCHEMBL28467031 | 0.73 | ALDH1A1 (0.48) | KMT2AMEN1LMNA | |
| Lactic Acid SCHEMBL28398200 | 0.73 | TP53 (0.42) | TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220071082-A1 | METHOD AND APPARATUS FOR DETERMINING AN AMOUNT OF NITROGEN-STABILIZING ADDITIVE | BASF SE (DE) | 2022-03-10 | — | — | US | disclosed |
| US-11246258-B2 | Method and vehicle for applying an agrochemical mixture to a working area of a field | BASF SE (DE) | 2022-02-15 | — | — | US | disclosed |
| WO-2022011298-A1 | MICROALGAE AND FERTILIZER MIXTURES AND METHODS OF USE THEREOF TO ENHANCE PLANT CHARACTERISTICS | HELIAE DEVELOPMENT LLC (US) | 2022-01-13 | — | — | WO | disclosed |
| EP-3923694-A1 | METHOD AND APPARATUS FOR DETERMINING AN AMOUNT OF NITROGEN-STABILIZING ADDITIVE | BASF SE (DE) | 2021-12-22 | — | — | EP | disclosed |
| CN-113423263-A | Method and apparatus for determining the amount of nitrogen stabilizing additive | 巴斯夫欧洲公司 | 2021-09-21 | — | — | CN | disclosed |
| CN-107426963-B | Method and vehicle for applying an agrochemical mixture to a field work area | 巴斯夫欧洲公司 | 2021-05-14 | — | — | CN | disclosed |
| WO-2020165818-A1 | METHOD AND APPARATUS FOR DETERMINING AN AMOUNT OF NITROGEN-STABILIZING ADDITIVE | BASF SE (DE) | 2020-08-20 | — | — | WO | disclosed |
| US-20200045878-A1 | METHOD AND VEHICLE FOR APPLYING AN AGROCHEMICAL MIXTURE TO A WORKING AREA OF A FIELD | BASF SE (DE) | 2020-02-13 | — | — | US | disclosed |
| CN-106470962-A | The combination of new nitrification and biological pesticide and the combination of (thio) phosphoric triamides and biological pesticide | 巴斯夫欧洲公司 | 2017-03-01 | — | — | CN | disclosed |