SCHEMBL2168022

SCHEMBL2168022

O=C(Nc1ccccc1)c1c(O)cccc1Cl

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYK2 P29597 4/20 0.58
JAK2 O60674 3/20 0.58
JAK1 P23458 3/20 0.58
CYP3A4 P08684 1/20 0.58
KMT2A Q03164 4/20 0.56
MEN1 O00255 3/20 0.56
LMNA P02545 2/20 0.56
KDM4E B2RXH2 1/20 0.56
TP53 P04637 1/20 0.56
HPGD P15428 1/20 0.56
HTT P42858 1/20 0.56
HSD17B10 Q99714 1/20 0.56
TAS1R3 Q7RTX0 1/20 0.54
TAS1R1 Q7RTX1 1/20 0.54
TAS1R2 Q8TE23 1/20 0.54
PTGS2 P35354 1/20 0.52
POLB P06746 2/20 0.51
GAA P10253 1/20 0.51
TMPRSS4 Q9NRS4 1/20 0.51
FADS1 O60427 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4154853 0.89 TYK2 (0.71) TYK2JAK2JAK1CYP3A4KMT2A
SCHEMBL9806566 0.87 MEN1 (0.66) KMT2AMEN1LMNAKDM4ETP53
SCHEMBL3810599 0.84 KDM4E (0.59) TYK2JAK2JAK1CYP3A4KMT2A
SCHEMBL3791414 0.83 SMO (0.61) TYK2JAK2JAK1CYP3A4KMT2A
SCHEMBL30230787 0.81 TYK2 (0.75) TYK2JAK2JAK1CYP3A4KMT2A
SCHEMBL2845491 0.81 F2R (0.63) TYK2JAK2JAK1CYP3A4KMT2A
SCHEMBL14991989 0.81 JAK1 (0.75) TYK2JAK2JAK1CYP3A4KMT2A
SCHEMBL9884060 0.81 TYK2 (0.75) TYK2JAK2JAK1CYP3A4KMT2A
SCHEMBL28448935 0.80 TYK2 (0.55) TYK2JAK2JAK1CYP3A4KMT2A
SCHEMBL19052112 0.79 HPGD (0.59) TYK2KMT2AMEN1LMNAKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3653303-B1 PIPETTE TIP RACK BIOTIX INC (US) 2025-02-26 EP disclosed
US-12201987-B2 Pipette tip rack BIOTIX, INC. (US) 2025-01-21 US disclosed
EP-4376673-B1 FILAMENTS FOR ORAL CARE IMPLEMENTS UNILEVER IP HOLDINGS B V (NL) 2025-01-01 EP disclosed
CN-118042960-A Filaments for oral care implements 联合利华知识产权控股有限公司 2024-05-14 CN disclosed
US-11590490-B2 Pipette tips BIOTIX, INC. (US) 2023-02-28 US disclosed
WO-2023006359-A1 FILAMENTS FOR ORAL CARE IMPLEMENTS UNILEVER IP HOLDINGS B.V. (NL) 2023-02-02 WO disclosed
EP-3628404-B1 PIPETTE TIP TRAYS BIOTIX INC (US) 2021-06-30 EP disclosed
EP-3831489-A1 PIPETTE TIPS Biotix, Inc. (US) 2021-06-09 EP disclosed
US-20210039086-A1 PIPETTE TIPS BIOTIX, INC. 2021-02-11 US disclosed
US-20210016290-A1 PIPETTE TIP RACK BIOTIX, INC. 2021-01-21 US disclosed
EP-1458419-A1 ANTIMICROBIAL CONTACT LENS CASE Novartis AG (CH) 2004-09-22 EP disclosed
US-20030176530-A1 Antimicrobial contact lens case LINDLEY KAREN FRANCES (US) 2003-09-18 US disclosed
WO-2003049776-A1 ANTIMICROBIAL CONTACT LENS CASE NOVARTIS AG (CH) 2003-06-19 WO disclosed
US-20030108761-A1 Anti-bacterial paper products EDDLEMON TAMMY (US) 2003-06-12 US disclosed
WO-2001070189-A1 METHOD AND COMPOSITION FOR SKIN LIGHTENING APPLYING CARBOXYLIC ACIDS UNILEVER PLC (GB) 2001-09-27 WO disclosed
US-6138315-A Antimicrobial active compounds CHESEBROUGH-POND'S USA CO., DIVISON OF CONOPCO, INC. (US) 2000-10-31 US disclosed
WO-1999035911-A1 ANTIMICROBIAL TOOTHBRUSH UNILEVER PLC (GB) 1999-07-22 WO disclosed
US-5919152-A Antibacterial swabs CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1999-07-06 US disclosed
US-5846215-A Antibacterial swabs CHESEBROUGH-POND'S USA CO., DIVISION OF CONOPCO, INC. (US) 1998-12-08 US disclosed
US-4022880-A ZINC IONS, 3,4,5-TRIBROMO-SALICYLANILIDE, QUATERNARY AMMONIUM COMPOUNDS LEVER BROTHERS COMPANY (US) 1977-05-10 US disclosed