Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMO | Q99835 | 4/20 | 0.61 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.60 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.60 |
| ▸ | JAK2 | O60674 | 3/20 | 0.58 |
| ▸ | TYK2 | P29597 | 2/20 | 0.58 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | JAK1 | P23458 | 1/20 | 0.58 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.58 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.58 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3478178 | 0.92 | ALDH1A1 (0.61) | SMOKCNK3KCNK9JAK2TYK2 | |
| SCHEMBL28259296 | 0.92 | ALDH1A1 (0.61) | SMOKCNK3KCNK9JAK2TYK2 | |
| SCHEMBL4154853 | 0.89 | TYK2 (0.71) | SMOKCNK3KCNK9JAK2TYK2 | |
| SCHEMBL29493359 | 0.89 | JAK2 (0.54) | SMOKCNK3KCNK9JAK2TYK2 | |
| SCHEMBL7188679 | 0.87 | ALDH1A1 (0.68) | CYP3A4ALDH1A1KMT2AMEN1TDP1 | |
| SCHEMBL1203522 | 0.85 | SMO (0.80) | SMOKCNK3KCNK9JAK2TYK2 | |
| SCHEMBL4155586 | 0.84 | JAK2 (0.73) | SMOKCNK3KCNK9JAK2TYK2 | |
| Water SCHEMBL27602058 | 0.84 | SMO (0.77) | SMOKCNK3KCNK9JAK2TYK2 | |
| SCHEMBL2168022 | 0.83 | TYK2 (0.58) | SMOKCNK3KCNK9JAK2TYK2 | |
| SCHEMBL5852388 | 0.83 | KLKB1 (0.72) | SMOKCNK3KCNK9JAK2TYK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2010-04-08 | — | — | US | disclosed |
| EP-1914221-A1 | PROCESS FOR PRODUCING BIARYL COMPOUND | Sumitomo Chemical Company, Limited (JP) | 2008-04-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100087680-A1 | METHOD FOR PRODUCING BIARYL COMPOUND | NISCH, BLVRB, BBOX1 | SMO 842/4885KCNK3 2193/4885KCNK9 2467/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.