Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 4/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.36 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2168187 | 0.91 | GFER (0.46) | CHRM2CHRM3GFERMEN1KMT2A | |
| SCHEMBL2168317 | 0.91 | GFER (0.39) | CHRM2CHRM3GFERMEN1KMT2A | |
| SCHEMBL2183275 | 0.85 | F10 (0.42) | CHRM2CHRM3MEN1KMT2ALMNA | |
| SCHEMBL2171166 | 0.85 | MEN1 (0.44) | CHRM2CHRM3MEN1KMT2ALMNA | |
| SCHEMBL2167126 | 0.85 | MAPT (0.41) | CHRM2CHRM3GFERMEN1KMT2A | |
| SCHEMBL18887266 | 0.85 | LMNA (0.35) | MEN1KMT2ALMNATP53MAPT | |
| SCHEMBL2184240 | 0.82 | HRH3 (0.44) | CHRM2CHRM3MEN1KMT2ALMNA | |
| SCHEMBL2168717 | 0.82 | SMN1; SMN2 (0.42) | CHRM2CHRM3LMNATP53MAPT | |
| SCHEMBL2167385 | 0.81 | CHRM2 (0.38) | CHRM2CHRM3GFERMEN1KMT2A | |
| SCHEMBL2180812 | 0.81 | NPC1 (0.43) | CHRM2CHRM3MEN1KMT2ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4732354-B2 | — | — | 2011-07-27 | — | — | JP | claimed |