Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2170383 | 0.92 | LTA4H (0.72) | LTA4HKCNH2 | |
| SCHEMBL2169281 | 0.90 | LTA4H (0.72) | LTA4HKCNH2 | |
| SCHEMBL2170467 | 0.84 | LTA4H (0.98) | LTA4HKCNH2 | |
| SCHEMBL14092981 | 0.84 | LTA4H (0.95) | LTA4HKCNH2 | |
| SCHEMBL2169881 | 0.84 | LTA4H (1.00) | LTA4HKCNH2 | |
| SCHEMBL2167835 | 0.83 | LTA4H (0.68) | LTA4HKCNH2 | |
| SCHEMBL2169352 | 0.83 | LTA4H (0.81) | LTA4HKCNH2 | |
| SCHEMBL2167877 | 0.83 | LTA4H (1.00) | LTA4HKCNH2 | |
| SCHEMBL2168655 | 0.83 | LTA4H (1.00) | LTA4HKCNH2 | |
| SCHEMBL2168218 | 0.83 | LTA4H (1.00) | LTA4HKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4726238-B2 | — | — | 2011-07-20 | — | — | JP | claimed |
| EP-1660492-A1 | BENZIMIDAZOLE, BENZTHIAZOLE AND BENZOXAZOLE DERIVATIVES AND THEIR USE AS LTA4H MODULATORS | Janssen Pharmaceutica N.V. (BE) | 2006-05-31 | — | — | EP | claimed |
| WO-2005012297-A1 | BENZIMIDAZOLE, BENZTHIAZOLE AND BENZOXAZOLE DERIVATIVES AND THEIR USE AS LTA4H MODULATORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-02-10 | — | — | WO | claimed |