SCHEMBL2168246

SCHEMBL2168246

ON=C(C(F)(F)F)C(F)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bicarbonate SCHEMBL9424929 0.87 CA2 (0.31)
SCHEMBL3943421 0.70
SCHEMBL17356130 0.67
SCHEMBL16605687 0.64
SCHEMBL8071572 0.64 MEN1 (0.31)
SCHEMBL11183978 0.62
SCHEMBL1448594 0.62
SCHEMBL14996082 0.62
SCHEMBL16026304 0.62
SCHEMBL263470 0.62

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101585756-A Method for preparing hexafluoroacetone SHANGHAI 3F NEW MATERIAL CO LT (CN) 2009-11-25 CN claimed
CN-1141623-A Production of hexafluoroacetone and its oxime MINNESOTA MINING & MFG (US) 1997-01-29 CN claimed
EP-0748308-A1 PRODUCTION OF HEXAFLUOROACETONE AND ITS OXIME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-12-18 EP claimed
US-5466879-A From perfluoroisobutene and trialkylamine, hydrolysis, solvent complex MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-11-14 US claimed
WO-1995023124-A1 PRODUCTION OF HEXAFLUOROACETONE AND ITS OXIME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-08-31 WO claimed
CN-107963996-B Method for preparing 3-trifluoromethyl isoxazole compound by one-pot method 江西师范大学 2021-06-11 CN disclosed
CN-107963996-A Method for preparing 3-trifluoromethyl isoxazole compound by one-pot method 江西师范大学 2018-04-27 CN disclosed
EP-2216320-B1 NOVEL CARBOXYLIC ACID ESTER, USE OF THE SAME, AND METHOD FOR PRODUCING THE SAME DAIKIN IND LTD (JP) 2016-08-03 EP disclosed
CN-103641692-B Preparation of novel fluorine-containing bisphenol compound UNIV BEIHANG 2015-07-08 CN disclosed
CN-101855196-B Novel carboxylic acid ester, use thereof, and method for producing same DAIKIN IND LTD 2014-07-30 CN disclosed
CN-102863319-B Novel carboxylic acid compound, use thereof, and process for producing the same DAIKIN IND LTD 2014-07-23 CN disclosed
EP-2039675-B1 ALPHA-FLUOROMETHOXYCARBOXYLIC ESTER, PROCESS FOR PRODUCING THEM, AND PROCESS FOR PRODUCING SEVOFLURANE DAIKIN IND LTD (JP) 2014-06-11 EP disclosed
US-5466879-A From perfluoroisobutene and trialkylamine, hydrolysis, solvent complex MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-11-14 US disclosed
US-5466879-A From perfluoroisobutene and trialkylamine, hydrolysis, solvent complex MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-11-14 US disclosed
WO-1995023124-A1 PRODUCTION OF HEXAFLUOROACETONE AND ITS OXIME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-08-31 WO disclosed
WO-1995023124-A1 PRODUCTION OF HEXAFLUOROACETONE AND ITS OXIME MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-08-31 WO disclosed
US-5276187-A Ketoxime carbonates and process for the synthesis of ketoxime carbonates generally ALLIEDSIGNAL INC. (US) 1994-01-04 US disclosed
WO-1993004037-A1 KETOXIME CARBONATES AND PROCESS FOR THEIR SYNTHESIS ALLIED-SIGNAL INC. (US) 1993-03-04 WO disclosed
US-4315019-A Novel aryltrifluoroethylamines and processes for producing the same SCIENCE UNION ET CIE (FR) 1982-02-09 US disclosed
US-4267345-A 2-//PYRROL-2-YL, THIEN-2-YL, OR FUR-2-YL/-ALPHA-TRIFLUOROALKYL-AMINOOXAZOLINES; HYPOTENSIVE AGENTS SCIENCE UNION ET CIE (FR) 1981-05-12 US disclosed