Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE5A | O76074 | 12/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21682583 | 1.00 | PDE5A (0.66) | PDE5A | |
| SCHEMBL21705400 | 1.00 | PDE5A (0.66) | PDE5A | |
| SCHEMBL31028931 | 1.00 | PDE5A (0.66) | PDE5A | |
| SCHEMBL21705399 | 0.95 | PDE5A (0.68) | PDE5A | |
| Citric Acid SCHEMBL30951847 | 0.95 | PDE5A (0.60) | PDE5A | |
| SCHEMBL23723932 | 0.93 | PDE5A (0.66) | PDE5A | |
| SCHEMBL21682625 | 0.93 | PDE5A (0.66) | PDE5A | |
| SCHEMBL21682626 | 0.93 | PDE5A (0.66) | PDE5A | |
| SCHEMBL21682595 | 0.93 | PDE5A (0.66) | PDE5A | |
| SCHEMBL29601312 | 0.93 | PDE5A (0.66) | PDE5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3833395-A1 | NITRIC OXIDE RELEASING PHOSPHODIESTERASE TYPE 5 INHIBITOR | Nicox S.A. (FR) | 2021-06-16 | — | — | EP | claimed |
| WO-2020030489-A1 | NITRIC OXIDE RELEASING PHOSPHODIESTERASE TYPE 5 INHIBITOR | NICOX S.A. (FR) | 2020-02-13 | — | — | WO | claimed |
| WO-2022090379-A1 | NO-PDE5 INHIBITOR FOR USE IN TREATING DRY AGE-RELATED MACULAR DEGENERATION, GEOGRAPHIC ATROPHY AND GLAUCOMA-ASSOCIATED NEURODEGENERATION | NICOX S.A. (FR) | 2022-05-05 | — | — | WO | disclosed |