2S,4R-4-Methylglutamate

2S,4R-4-Methylglutamate

SCHEMBL21682833

C[C@H](CC(N)C(=O)O)C(=O)O

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.68
SLC1A3 P43003 6/20 0.60
SLC1A2 P43004 6/20 0.60
SLC1A1 P43005 6/20 0.60
ENPEP Q07075 2/20 0.58
GRIK1 P39086 3/20 0.50
GRIK2 Q13002 2/20 0.50
GABRR1 P24046 2/20 0.48
GRIA2 P42262 2/20 0.47
GRIA4 P48058 2/20 0.47
GRIK3 Q13003 2/20 0.47
GRIK5 Q16478 2/20 0.47
GRIA1 P42261 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2S,4R-4-Methylglutamate SCHEMBL1060785 1.00 SLC7A5 (0.68) SLC7A5SLC1A3SLC1A2SLC1A1ENPEP
2S,4R-4-Methylglutamate SCHEMBL30990075 1.00 SLC7A5 (0.68) SLC7A5SLC1A3SLC1A2SLC1A1ENPEP
2S,4R-4-Methylglutamate SCHEMBL2263577 1.00 SLC7A5 (0.68) SLC7A5SLC1A3SLC1A2SLC1A1ENPEP
2S,4R-4-Methylglutamate SCHEMBL594187 1.00 SLC7A5 (0.68) SLC7A5SLC1A3SLC1A2SLC1A1ENPEP
2S,4R-4-Methylglutamate SCHEMBL7064898 1.00 SLC7A5 (0.68) SLC7A5SLC1A3SLC1A2SLC1A1ENPEP
2S,4R-4-Methylglutamate SCHEMBL7778018 1.00 SLC7A5 (0.68) SLC7A5SLC1A3SLC1A2SLC1A1ENPEP
2S,4R-4-Methylglutamate SCHEMBL12497563 1.00 SLC7A5 (0.68) SLC7A5SLC1A3SLC1A2SLC1A1ENPEP
2S,4R-4-Methylglutamate SCHEMBL250314 1.00 SLC7A5 (0.68) SLC7A5SLC1A3SLC1A2SLC1A1ENPEP
2S,4R-4-Methylglutamate SCHEMBL1133372 1.00 SLC7A5 (0.68) SLC7A5SLC1A3SLC1A2SLC1A1ENPEP
2S,4R-4-Methylglutamate SCHEMBL8993381 0.97 SLC7A5 (0.65) SLC7A5SLC1A3SLC1A2SLC1A1ENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3833676-A1 POLYPEPTIDES SELF-ASSEMBLING INTO NANOPARTICLES ETH Zürich (CH) 2021-06-16 EP disclosed
WO-2020030654-A1 POLYPEPTIDES SELF-ASSEMBLING INTO NANOPARTICLES ETH Zürich (CH) 2020-02-13 WO disclosed