2S,4R-4-Methylglutamate

2S,4R-4-Methylglutamate

SCHEMBL2263577

C[C@@H](C[C@H](N)C(=O)O)C(=O)O

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.68
SLC1A3 P43003 6/20 0.60
SLC1A2 P43004 6/20 0.60
SLC1A1 P43005 6/20 0.60
ENPEP Q07075 2/20 0.58
GRIK1 P39086 3/20 0.50
GRIK2 Q13002 2/20 0.50
GABRR1 P24046 2/20 0.48
GRIA2 P42262 2/20 0.47
GRIA4 P48058 2/20 0.47
GRIK3 Q13003 2/20 0.47
GRIK5 Q16478 2/20 0.47
GRIA1 P42261 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
2S,4R-4-Methylglutamate SCHEMBL1060785 1.00 SLC7A5 (0.68) SLC7A5SLC1A3SLC1A2SLC1A1ENPEP
2S,4R-4-Methylglutamate SCHEMBL30990075 1.00 SLC7A5 (0.68) SLC7A5SLC1A3SLC1A2SLC1A1ENPEP
2S,4R-4-Methylglutamate SCHEMBL594187 1.00 SLC7A5 (0.68) SLC7A5SLC1A3SLC1A2SLC1A1ENPEP
2S,4R-4-Methylglutamate SCHEMBL7064898 1.00 SLC7A5 (0.68) SLC7A5SLC1A3SLC1A2SLC1A1ENPEP
2S,4R-4-Methylglutamate SCHEMBL7778018 1.00 SLC7A5 (0.68) SLC7A5SLC1A3SLC1A2SLC1A1ENPEP
2S,4R-4-Methylglutamate SCHEMBL12497563 1.00 SLC7A5 (0.68) SLC7A5SLC1A3SLC1A2SLC1A1ENPEP
2S,4R-4-Methylglutamate SCHEMBL250314 1.00 SLC7A5 (0.68) SLC7A5SLC1A3SLC1A2SLC1A1ENPEP
2S,4R-4-Methylglutamate SCHEMBL1133372 1.00 SLC7A5 (0.68) SLC7A5SLC1A3SLC1A2SLC1A1ENPEP
2S,4R-4-Methylglutamate SCHEMBL21682833 1.00 SLC7A5 (0.68) SLC7A5SLC1A3SLC1A2SLC1A1ENPEP
2S,4R-4-Methylglutamate SCHEMBL8993381 0.97 SLC7A5 (0.65) SLC7A5SLC1A3SLC1A2SLC1A1ENPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552839-B2 Cyclic peptides for protection against respiratory syncytial virus VIROMETIX AG (CH) 2026-02-17 US claimed
US-20240287143-A1 CYCLIC PEPTIDES FOR PROTECTION AGAINST RESPIRATORY SYNCYTIAL VIRUS Universität Zürich (CH) 2024-08-29 US claimed
EP-4295866-A2 CYCLIC PEPTIDES FOR PROTECTION AGAINST RESPIRATORY SYNCYTIAL VIRUS Virometix AG (CH) 2023-12-27 EP claimed
EP-3638284-B1 CYCLIC PEPTIDES FOR PROTECTION AGAINST RESPIRATORY SYNCYTIAL VIRUS VIROMETIX AG (CH) 2023-08-30 EP claimed
US-11680085-B2 Cyclic peptides for protection against respiratory syncytial virus VIROMETIX AG (CH) 2023-06-20 US claimed
CN-112654366-A Methods of treating or inhibiting the onset of huntington's disease 罗切斯特大学 2021-04-13 CN claimed
EP-0809624-B1 ALKYLCARBOXY AMINO ACIDS-MODULATORS OF THE KAINATE RECEPTOR BEARSDEN BIO INC (US) 2001-08-29 EP claimed
US-5731348-A NERVOUS SYSTEM DISORDERS BEARSDEN BIO, INC. (US) 1998-03-24 US claimed
EP-0809624-A1 ALKYLCARBOXY AMINO ACIDS-MODULATORS OF THE KAINATE RECEPTOR Bearsden Bio, Inc. (US) 1997-12-03 EP claimed
WO-1996025387-A1 ALKYLCARBOXY AMINO ACIDS-MODULATORS OF THE KAINATE RECEPTOR SYMPHONY PHARMACEUTICALS, INC. (US) 1996-08-22 WO claimed
US-20260137767-A1 LIPOPEPTIDE BUILDING BLOCKS AND SYNTHETIC VIRUS-LIKE PARTICLES VIROMETIX AG (CH) 2026-05-21 US disclosed
US-12552839-B2 Cyclic peptides for protection against respiratory syncytial virus VIROMETIX AG (CH) 2026-02-17 US disclosed
US-20260028375-A1 POLYPEPTIDES SELF-ASSEMBLING INTO NANOPARTICLES ETH ZUERICH (CH) 2026-01-29 US disclosed
US-20250376709-A1 PAPB AS A BIMOIETY-DEPENDENT THIOETHER INSTALLATION TOOL UNIV UTAH RES FOUND (US) 2025-12-11 US disclosed
US-12465633-B2 Lipopeptide building blocks and synthetic virus-like particles VIROMETIX AG (CH) 2025-11-11 US disclosed
WO-2007116724-A1 PROCESS FOR PRODUCTION OF 1β-METHYLCARBAPENEM MEIJI SEIKA KAISHA, LTD. (JP) 2007-10-18 WO disclosed
EP-0809624-B1 ALKYLCARBOXY AMINO ACIDS-MODULATORS OF THE KAINATE RECEPTOR BEARSDEN BIO INC (US) 2001-08-29 EP disclosed
US-5731348-A NERVOUS SYSTEM DISORDERS BEARSDEN BIO, INC. (US) 1998-03-24 US disclosed
EP-0809624-A1 ALKYLCARBOXY AMINO ACIDS-MODULATORS OF THE KAINATE RECEPTOR Bearsden Bio, Inc. (US) 1997-12-03 EP disclosed
WO-1996025387-A1 ALKYLCARBOXY AMINO ACIDS-MODULATORS OF THE KAINATE RECEPTOR SYMPHONY PHARMACEUTICALS, INC. (US) 1996-08-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11680085-B2 Cyclic peptides for protection against respiratory syncytial virus VIP, LNPEP, CSTB SLC7A5 2179/4885SLC1A3 4201/4885SLC1A2 4780/4885
US-20260137767-A1 LIPOPEPTIDE BUILDING BLOCKS AND SYNTHETIC VIRUS-LIKE PARTICLES VSIR, LRBA, CD74 SLC7A5 2164/4885SLC1A3 4257/4885SLC1A2 4754/4885
US-20260028375-A1 POLYPEPTIDES SELF-ASSEMBLING INTO NANOPARTICLES PHAX, TPX2, MLX SLC7A5 192/4885SLC1A3 205/4885SLC1A2 459/4885
US-12465633-B2 Lipopeptide building blocks and synthetic virus-like particles VSIR, CXCL10, SGTA SLC7A5 2069/4885SLC1A3 4134/4885SLC1A2 4575/4885
US-20240287143-A1 CYCLIC PEPTIDES FOR PROTECTION AGAINST RESPIRATORY SYNCYTIAL VIRUS VIP, QPCT, QPCTL SLC7A5 196/4885SLC1A3 685/4885SLC1A2 2572/4885
US-12552839-B2 Cyclic peptides for protection against respiratory syncytial virus CTH, VIP, CXCL10 SLC7A5 37/4885SLC1A3 404/4885SLC1A2 1464/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.