Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL11358653 | 0.94 | CA4 (0.50) | — | |
| Bicarbonate SCHEMBL18155 | 0.94 | — | — | |
| Bicarbonate SCHEMBL1331862 | 0.94 | — | — | |
| Bicarbonate SCHEMBL2364135 | 0.88 | — | — | |
| Bicarbonate SCHEMBL3238836 | 0.88 | CA4 (0.46) | — | |
| Bicarbonate SCHEMBL9503548 | 0.88 | — | — | |
| Bicarbonate SCHEMBL7516959 | 0.88 | CA4 (0.46) | — | |
| Bicarbonate SCHEMBL8954332 | 0.88 | CA4 (0.46) | — | |
| Bicarbonate SCHEMBL1870014 | 0.88 | CA4 (0.46) | — | |
| Bicarbonate SCHEMBL4588623 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1764376-A | Reduction amination by levulinic acid and nitro compound is produced 5-methyl-N-aryl-2-Pyrrolidone and 5-methyl-N-alkyl-2-Pyrrolidone | DU PONT (US) | 2006-04-26 | — | — | CN | claimed |
| CN-1214023-C | Process for producing benzo-fused heterocycle | MERCK PATENT GMBH (DE) | 2005-08-10 | — | — | CN | claimed |
| CN-1422265-A | Process for producing benzo-fused heterocycle | MERCK PATENT GMBH (DE) | 2003-06-04 | — | — | CN | claimed |
| US-20260108497-A1 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICALC., LTD. (JP) | 2026-04-23 | — | — | US | disclosed |
| US-20240148699-A1 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-05-09 | — | — | US | disclosed |
| US-20220265613-A1 | OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-08-25 | — | — | US | disclosed |
| US-11273168-B2 | Methods of treating anxiety by administering a substituted quinolone | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2022-03-15 | — | — | US | disclosed |
| US-11214559-B2 | Method for producing 2,5-bis(aminomethyl)furan | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2022-01-04 | — | — | US | disclosed |
| EP-3696173-B1 | METHOD FOR PRODUCING 2,5-BIS(AMINOMETHYL) TETRAHYDROFURAN | MITSUBISHI GAS CHEMICAL CO (JP) | 2021-12-22 | — | — | EP | disclosed |
| EP-3656766-B1 | METHOD FOR PRODUCING 2,5-BIS(AMINOMETHYL)FURAN | MITSUBISHI GAS CHEMICAL CO (JP) | 2021-09-15 | — | — | EP | disclosed |
| US-20210221782-A1 | METHOD FOR PRODUCING 2,5-BIS(AMINOMETHYL)TETRAHYDROFURAN | MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) | 2021-07-22 | — | — | US | disclosed |
| US-4524028-A | PENICILLINS | CIBA-GEIGY CORPORATION (US) | 1985-06-18 | — | — | US | disclosed |
| US-4518533-A | Azetidinone-4-disulfides as intermediates for thia-aza compounds with a beta-lactam ring | CIBA GEIGY CORPORATION (US) | 1985-05-21 | — | — | US | disclosed |
| US-4515717-A | INTERMEDIATES FOR 6-UNSUBSTITUTED PENICILLIN ANTIOBIOTICS | CIBA GEIGY CORPORATION (US) | 1985-05-07 | — | — | US | disclosed |
| US-4500457-A | TREATING AN ACYLOXYAZETIDINONE WITH MERCAPTO COMPOUND, GLYOYLIC ESTER, HALOGENATION AGENT, AND PHOSPHINE COMPOUNT THEN CYCLIZATION | CIBA-GEIGY CORPORATION (US) | 1985-02-19 | — | — | US | disclosed |
| US-4447360-A | Intermediates for thia-aza compounds with a β-lactam ring | CIBA-GEIGY CORPORATION (US) | 1984-05-08 | — | — | US | disclosed |
| US-4331676-A | 2-PENEM COMPOUNDS UNSUBSTITUTED IN THE 6 POSITION | CIBA-GEIGY CORPORATION (US) | 1982-05-25 | — | — | US | disclosed |
| US-4220587-A | BACTERICIDES | MITSUBISHI CHEMICAL INDUSTRIES, LIMITED (JP) | 1980-09-02 | — | — | US | disclosed |
| US-4179437-A | Amino acid derivatives of 6-(2-amino-2-arylacetamido) penicillanic acids | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1979-12-18 | — | — | US | disclosed |
| US-4111932-A | BACTERICIDE | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JP) | 1978-09-05 | — | — | US | disclosed |