Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL384201 | 0.94 | — | — | |
| Bicarbonate SCHEMBL29118179 | 0.94 | CA4 (0.50) | — | |
| Bicarbonate SCHEMBL9503556 | 0.94 | CA4 (0.50) | — | |
| Bicarbonate SCHEMBL93792 | 0.88 | — | — | |
| Bicarbonate SCHEMBL10394676 | 0.88 | — | — | |
| Bicarbonate SCHEMBL216839 | 0.88 | — | — | |
| Bicarbonate SCHEMBL93791 | 0.88 | CA4 (0.46) | — | |
| Bicarbonate SCHEMBL7095611 | 0.88 | — | — | |
| Bicarbonate SCHEMBL1996859 | 0.88 | — | — | |
| Bicarbonate SCHEMBL932087 | 0.88 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0330380-B1 | NOVEL INDANOXYACETIC ACID DERIVATIVES AND PROCESSES FOR PREPARING THE SAME | TANABE SEIYAKU CO., LTD. (JP) | 1993-06-23 | — | — | EP | disclosed |
| US-4975460-A | INHIBITION OF PLATELET AGGREGATION | TANABE SEIYAKU CO., LTD. (JP) | 1990-12-04 | — | — | US | disclosed |
| EP-0330380-A2 | Novel indanoxyacetic acid derivatives and processes for preparing the same | TANABE SEIYAKU CO., LTD. (JP) | 1989-08-30 | — | — | EP | disclosed |