Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR9 | P51686 | 17/20 | 0.74 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | HTT | P42858 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.53 |
| ▸ | CCR2 | P41597 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL344936 | 0.90 | CCR9 (0.86) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL28160 | 0.89 | LMNA (0.73) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL13850920 | 0.88 | CCR9 (0.72) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL342185 | 0.85 | CCR9 (0.79) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL344098 | 0.85 | CCR9 (1.00) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL343170 | 0.85 | CCR9 (1.00) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL2169219 | 0.85 | CCR9 (1.00) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL15761703 | 0.85 | CCR9 (0.79) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL2168505 | 0.84 | CCR9 (1.00) | CCR9LMNAHTTTP53MAPT | |
| SCHEMBL27309 | 0.83 | CCR9 (0.80) | CCR9LMNAHTTTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1798223-B2 | Aryl sulfonamides | CHEMOCENTRYX INC (US) | 2014-07-30 | — | — | EP | claimed |
| EP-1798223-B1 | Aryl sulfonamides | CHEMOCENTRYX INC (US) | 2011-07-20 | — | — | EP | claimed |