SCHEMBL21689062

SCHEMBL21689062

CC(C)(C)OC(=O)C(Cc1ccc(N)cc1)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.58

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 2/20 0.47
TP53 P04637 2/20 0.47
KMT2A Q03164 1/20 0.45
PTPN1 P18031 3/20 0.44
MDM2 Q00987 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29528888 1.00 MDM4 (0.47) MDM4TP53KMT2APTPN1MDM2
SCHEMBL28741504 0.92 MDM4 (0.52) MDM4TP53MDM2
SCHEMBL28741502 0.92 MDM4 (0.52) MDM4TP53MDM2
SCHEMBL28741474 0.91 MDM4 (0.47) MDM4TP53PTPN1MDM2
SCHEMBL7338800 0.91 MDM4 (0.48) MDM4TP53KMT2APTPN1MDM2
SCHEMBL29633851 0.91 MDM2 (0.48) MDM4TP53KMT2APTPN1MDM2
SCHEMBL1957887 0.91 MDM4 (0.48) MDM4TP53KMT2APTPN1MDM2
SCHEMBL12568249 0.91 CTSS (0.52) MDM4TP53PTPN1MDM2
SCHEMBL12568250 0.91 CTSS (0.52) MDM4TP53PTPN1MDM2
SCHEMBL29351891 0.91 MDM4 (0.48) MDM4TP53KMT2APTPN1MDM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3604326-A1 PEPTIDE COMPOUND AND METHOD FOR PRODUCING SAME, COMPOSITION FOR SCREENING USE, AND METHOD FOR SELECTING PEPTIDE COMPOUND FUJIFILM Corporation (JP) 2020-02-05 EP disclosed