SCHEMBL21690293

SCHEMBL21690293

C[C@@H](NS(=O)(=O)CCCO)c1cccc(OCCC(F)(F)F)c1

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ DUT P33316 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12630552 0.83 DUT (0.64) DUT
SCHEMBL21690963 0.82 DUT (0.62) DUT
SCHEMBL12630548 0.79 DUT (0.66) DUT
SCHEMBL20361933 0.79 DUT (0.66) DUT
SCHEMBL12630555 0.79 DUT (0.62) DUT
SCHEMBL21690344 0.77 DUT (0.65) DUT
SCHEMBL21690728 0.77 DUT (0.68) DUT
SCHEMBL13606345 0.76 DUT (0.62) DUT
SCHEMBL22170148 0.76 DUT (0.52) DUT
SCHEMBL21691001 0.76 DUT (0.67) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11247984-B2 Uracil containing compounds CV6 THERAPEUTICS (NI) LIMITED (GB) 2022-02-15 — — US disclosed
US-20200039966-A1 URACIL CONTAINING COMPOUNDS CV6 THERAPEUTICS (NI) LIMITED (GB) 2020-02-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200039966-A1 URACIL CONTAINING COMPOUNDS UNG, DPYD, DUT DUT 3/4885
US-11247984-B2 Uracil containing compounds UNG, DPYD, DUT DUT 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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