SCHEMBL21690388

SCHEMBL21690388

CC(C)COc1cc([C@@H](C)NS(=O)(=O)/C=C/COCC(C)(C)C)ccc1F

nearest known ligand 0.40

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ DUT P33316 13/20 0.40
▸ TRPV1 Q8NER1 1/20 0.33
▸ CA1 P00915 1/20 0.33
▸ CA2 P00918 1/20 0.33
▸ ACHE P22303 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21690668 0.93 DUT (0.47) DUTCA1CA2ACHE
SCHEMBL21690656 0.87 DUT (0.50) DUT
SCHEMBL18374298 0.80 DUT (0.49) DUT
SCHEMBL18374343 0.78 DUT (0.45) DUT
SCHEMBL20374147 0.77 DUT (0.41) DUT
SCHEMBL21690650 0.73 DUT (0.67) DUT
SCHEMBL20374123 0.73 DUT (0.51) DUTCA1CA2ACHE
SCHEMBL20351703 0.73 DUT (0.53) DUT
SCHEMBL20376272 0.72 DUT (0.44) DUT
SCHEMBL20351695 0.72 DUT (0.53) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11247984-B2 Uracil containing compounds CV6 THERAPEUTICS (NI) LIMITED (GB) 2022-02-15 — — US disclosed
US-20200039966-A1 URACIL CONTAINING COMPOUNDS CV6 THERAPEUTICS (NI) LIMITED (GB) 2020-02-06 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200039966-A1 URACIL CONTAINING COMPOUNDS UNG, DPYD, DUT DUT 3/4885TRPV1 4784/4885CA1 2942/4885
US-11247984-B2 Uracil containing compounds UNG, DPYD, DUT DUT 3/4885TRPV1 4784/4885CA1 2942/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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