SCHEMBL21691007

SCHEMBL21691007

CC(C)COc1cc(C(C)(C)NS(=O)(=O)CCCCCN2CCC(=O)NC2=O)ccc1F

nearest known ligand 0.66

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
DUT P33316 19/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18374314 0.92 DUT (0.78) DUT
SCHEMBL21690726 0.89 DUT (0.56) DUT
SCHEMBL18374331 0.88 DUT (0.85) DUT
SCHEMBL21690953 0.86 DUT (0.71) DUT
SCHEMBL21690954 0.86 DUT (0.71) DUT
SCHEMBL20361926 0.85 DUT (0.54) DUT
SCHEMBL29387085 0.85 DUT (0.54) DUT
SCHEMBL18374676 0.83 DUT (0.86) DUT
SCHEMBL20560444 0.83 DUT (0.68) DUT
SCHEMBL18374675 0.83 DUT (0.68) DUT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200039966-A1 URACIL CONTAINING COMPOUNDS CV6 THERAPEUTICS (NI) LIMITED (GB) 2020-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200039966-A1 URACIL CONTAINING COMPOUNDS UNG, DPYD, DUT DUT 3/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.