Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20147765 | 0.99 | MAP3K12 (0.60) | MAP3K12PIK3CA | |
| SCHEMBL20115399 | 0.98 | MAP3K12 (0.60) | MAP3K12PIK3CA | |
| SCHEMBL21695315 | 0.92 | MAP3K12 (0.62) | MAP3K12PIK3CA | |
| SCHEMBL21695290 | 0.91 | MAP3K12 (0.61) | MAP3K12PIK3CA | |
| SCHEMBL21695318 | 0.90 | MAP3K12 (0.61) | MAP3K12PIK3CA | |
| SCHEMBL21695313 | 0.90 | MAP3K12 (0.60) | MAP3K12PIK3CA | |
| SCHEMBL21695275 | 0.89 | MAP3K12 (0.64) | MAP3K12PIK3CA | |
| SCHEMBL21695277 | 0.88 | MAP3K12 (0.61) | MAP3K12PIK3CA | |
| SCHEMBL21695268 | 0.88 | MAP3K12 (0.60) | MAP3K12PIK3CA | |
| SCHEMBL21695279 | 0.88 | MAP3K12 (0.66) | MAP3K12PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE47848-E1 | Biheteroaryl compounds and uses thereof | GENENTECH, INC. (US) | 2020-02-11 | — | — | US | disclosed |