Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 6/20 | 0.41 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CTSL | P07711 | 2/20 | 0.36 |
| ▸ | CTSB | P07858 | 2/20 | 0.36 |
| ▸ | CETP | P11597 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3426595 | 0.89 | TSHR (0.44) | ALDH1A1CYP3A4TSHRMAPK1TDP1 | |
| SCHEMBL16177916 | 0.88 | CTSK (0.42) | CTSKSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL15541563 | 0.84 | CTSK (0.43) | CTSKSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL13672306 | 0.84 | TSHR (0.44) | CTSKSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL28998085 | 0.81 | CETP (0.45) | MEN1KMT2AMAPK1CETP | |
| SCHEMBL30524953 | 0.81 | CETP (0.42) | CTSKSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL8917997 | 0.80 | SLC1A3 (0.41) | CTSKSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL28161709 | 0.80 | TSHR (0.35) | CTSKSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL11731022 | 0.79 | CETP (0.41) | CTSKSLC1A3SLC1A2SLC1A1MEN1 | |
| SCHEMBL11731029 | 0.79 | CETP (0.41) | CTSKSLC1A3SLC1A2SLC1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10556907-B2 | Fused heterocyclic compounds as S1P modulators | AbbVie Deutschland GmbH & Co. KG (DE) | 2020-02-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10556907-B2 | Fused heterocyclic compounds as S1P modulators | S1PR1, S1PR2, S1PR3 | CTSK 2564/4885SLC1A3 4123/4885SLC1A2 4408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.