Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VHL | P40337 | 9/20 | 0.61 |
| ▸ | ELOC | Q15369 | 3/20 | 0.53 |
| ▸ | ELOB | Q15370 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | KLK7 | P49862 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15126111 | 1.00 | VHL (0.61) | VHLELOCELOBTSHRPOLB | |
| SCHEMBL15126148 | 0.91 | VHL (0.63) | VHLELOCELOBTSHRPOLB | |
| SCHEMBL21696485 | 0.90 | VHL (0.49) | VHLELOCELOBTSHRPOLB | |
| SCHEMBL15126024 | 0.89 | VHL (0.59) | VHLELOCELOBTSHRPOLB | |
| SCHEMBL16277201 | 0.84 | VHL (0.45) | VHLPOLBALDH1A1 | |
| SCHEMBL21696680 | 0.83 | VHL (0.82) | VHLELOCELOB | |
| SCHEMBL16277195 | 0.83 | VHL (0.82) | VHLELOCELOB | |
| SCHEMBL15125974 | 0.83 | VHL (0.82) | VHLELOCELOB | |
| SCHEMBL15125982 | 0.83 | VHL (0.60) | VHLELOCELOBALDH1A1 | |
| SCHEMBL15126072 | 0.82 | VHL (0.69) | VHLELOCELOBTSHRPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3608317-A1 | COMPOUNDS & METHODS FOR THE ENHANCED DEGRADATION OF TARGETED PROTEINS & OTHER POLYPEPTIDES BY AN E3 UBIQUITIN LIGASE | Yale University (US) | 2020-02-12 | — | — | EP | disclosed |