Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.36 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | STAT3 | P40763 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20741882 | 0.88 | CYP2A6 (0.40) | L3MBTL1MAPTMAPK1TDP1BRD4 | |
| SCHEMBL21697590 | 0.88 | PTGER1 (0.43) | MRGPRX4L3MBTL1MAPTSMN1; SMN2LMNA | |
| SCHEMBL16020950 | 0.83 | MAPT (0.32) | L3MBTL1MAPTTDP1SMN1; SMN2LMNA | |
| SCHEMBL16018676 | 0.80 | AKR1B1 (0.32) | RAB9A | |
| SCHEMBL21697633 | 0.80 | SLC5A2 (0.40) | SMN1; SMN2STAT3HTTMAOBHTR2A | |
| SCHEMBL21697564 | 0.79 | FFAR1 (0.37) | FFAR1FFAR4MRGPRX4L3MBTL1MAPT | |
| SCHEMBL7632432 | 0.77 | TDP1 (0.47) | FFAR4L3MBTL1MAPTMAPK1TDP1 | |
| SCHEMBL20741835 | 0.77 | SLC5A2 (0.44) | — | |
| SCHEMBL21697598 | 0.75 | SLC5A2 (0.42) | MRGPRX4SMN1; SMN2PTGER1RAB9A | |
| SCHEMBL13271966 | 0.73 | CYP2A6 (0.40) | L3MBTL1MAPTTDP1SMN1; SMN2RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968258-B1 | DUAL SGLT1/SGLT2 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-02-12 | — | — | EP | disclosed |