Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 13/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | CCR5 | P51681 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21697612 | 0.89 | SMN1; SMN2 (0.37) | SMN1; SMN2MAPTHTTL3MBTL1RAB9A | |
| SCHEMBL21697564 | 0.89 | FFAR1 (0.37) | PTGER1MRGPRX4SMN1; SMN2LMNAMAPT | |
| SCHEMBL16020955 | 0.84 | KDM4E (0.36) | SMN1; SMN2LMNAHTTL3MBTL1 | |
| SCHEMBL16018679 | 0.80 | CYP2A6 (0.31) | — | |
| SCHEMBL21697590 | 0.79 | PTGER1 (0.43) | PTGER1MRGPRX4CCR5SMN1; SMN2LMNA | |
| SCHEMBL20741824 | 0.78 | ABCB1 (0.41) | SMN1; SMN2MAPTRAB9A | |
| SCHEMBL21697595 | 0.77 | SMN1; SMN2 (0.37) | PTGER1SMN1; SMN2LMNAMAPTL3MBTL1 | |
| SCHEMBL21697537 | 0.75 | MRGPRX4 (0.36) | PTGER1MRGPRX4SMN1; SMN2RAB9A | |
| SCHEMBL21697661 | 0.75 | HPGD (0.45) | PPARASMN1; SMN2MAPTHTTL3MBTL1 | |
| SCHEMBL16020939 | 0.75 | MAPT (0.36) | PPARALMNAMAPTL3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2968258-B1 | DUAL SGLT1/SGLT2 INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2020-02-12 | — | — | EP | disclosed |